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作 者:姚迎春 王玲[1] 韩丽英[1] YAO Ying-chun;WANG Ling;HAN Li-ying(Department of Obstetrics and Gynecology,The Second Hospital of Jilin University,Changchun 130041,China)
机构地区:[1]吉林大学第二医院妇产科
出 处:《国际生殖健康/计划生育杂志》2019年第6期483-485,F0003,共4页Journal of International Reproductive Health/Family Planning
摘 要:卵巢生长性畸胎瘤综合征(growing teratoma syndrome,GTS)作为一种罕见并发症,其特点是在化疗期间或化疗结束后,肿瘤标志物正常,但肿瘤的大小或数目增加或两者同时增加,手术标本病理检查提示仅存在成熟畸胎瘤成分。诊断明确,但由于发病率低,临床医生对其认识不足,易被误解为疾病进展。虽然该病的确切病因和发病机制仍未明确,但临床特征已明确,作为一种耐化疗和放疗的疾病,外科手术是最好的治疗方式。报道1例卵巢GTS,并复习相关文献,为临床诊断及治疗提供参考。Ovarian growing teratoma syndrome(GTS), as a rare complication, is characterized by the increase in tumor size or tumor number, or both, with the normalization of tumour markers during or after chemotherapy or radiological therapy. Histopathological test showed a mature teratoma without any malignant component. Although the diagnosis is clear, many oncologists often misinterpret because of its rarity. The exact etiology and pathogenesis of this disease are still unclear. Surgery is the best treatment as this disease is resistant to chemotherapy and radiation. We reported a case of GTS, and reviewed relevant literatures, to provide a reference for clinical diagnosis and treatment.
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