幽门螺杆菌感染情况与胆囊结石胆囊炎和胆囊息肉的关联性分析  

The relationship between helicobacter pylori infection and cholecystolithiasis,cholecystitis and gallbladder polyps

作　　者：张玲[1] 张业 张雪[1] 朱亚萍 马麒 白飞虎[3] ZHANG Ling;ZHANG Ye;ZHANG Xue(Department of Gastroenterology,the First Affiliated Hospital of Northwest University for Nationalities,Yinchuan 750021,China)

机构地区：[1]西北民族大学第一附属医院消化内科,银川750021 [2]河南大学第一附属医院普外科,开封475000 [3]宁夏回族自治区人民医院消化内科,银川750021

出　　处：《中国临床新医学》2019年第11期1185-1188,共4页CHINESE JOURNAL OF NEW CLINICAL MEDICINE

基　　金：宁夏消化疾病临床医学研究中心课题(编号:2018CXPT0075)

摘　　要：目的分析幽门螺杆菌(Hp)感染与胆囊结石、胆囊炎和胆囊息肉的关联性,探讨根除Hp在预防胆囊疾病的临床价值。方法回顾性收集2018-06~2018-12在该院以腹部不适症状就诊并行Hp尿素酶抗体检测的临床病例资料962例。分析胆囊炎、胆囊结石、胆囊息肉的发生与Hp感染的关联性,以及不同Hp感染情况下相关胆囊疾病的临床特征。结果Hp阳性组433例,Hp阴性组529例,Hp感染率为45.01%(433/962)。Hp阳性组的平均年龄、患胆囊结石及胆囊炎的人数比例大于Hp阴性组,差异有统计学意义(P<0.05)。在胆囊结石患者中,Hp阳性者的总胆固醇水平高于Hp阴性者,差异有统计学意义(P<0.05)。在胆囊炎患者中,Hp阳性者平均白细胞计数水平高于Hp阴性者,差异有统计学意义(P<0.05)。结论Hp感染可能与胆囊炎、胆囊结石的发生、发展存在一定的关联性。Objective To study the relationship between helicobacter pylori(Hp)infection and cholecystolithiasis,cholecystitis and gallbladder polyps,and to explore the clinical value of Hp eradication in prevention of gallbladder diseases.Methods Nine hundred and sixty-two cases with abdominal discomfort and detection of Hp urease antibody were collected in our hospital from June 2018 to December 2018 and their clinical data were retrospectively analyzed.The relationship between the occurrence of cholecystitis,cholecystolithiasis and gallbladder polyps and Hp infection,and the clinical characteristics of gallbladder diseases under different Hp infections were analyzed.Results In this study,there were 433 cases in the Hp positive group and 529 cases in the Hp negative group,and the Hp infection rate was 45.01%(433/962).The average age of the patients and the proportion of the patients with cholecystolithiasis and cholecystitis in the Hp positive group were significantly larger than those in the Hp negative group(P<0.05).In the patients with cholecystolithiasis,the total cholesterol level of the Hp positive patients was significantly higher than that of the Hp negative patients(P<0.05).In the patients with cholecystitis,the average white blood cell count of the Hp positive patients was significantly higher than that of the Hp negative patients(P<0.05).Conclusion Hp infection may be associated with the occurrence and development of cholecystitis and cholecystolithiasis.

关 键 词：幽门螺杆菌 胆囊炎 胆囊结石 胆囊息肉 

分 类 号：R575[医药卫生—消化系统]