透明托盘结合生物活性玻璃对诊室漂白治疗所致牙齿敏感的疗效评价  

Effect evaluation of BGs and transparent tray desensitizer application prior to in-office bleaching

作　　者：马骞[1] 宋海洋 叶莺[1] 李次会 陈亚明[1] MA Qian;SONG Haiyang;YE Ying;LI Cihui;CHEN Yaming(Jiangsu Key Laboratory of Oral Diseases,Nanjing Medical University,Department of Polyclinics,Affiliated Hospital of Stomatology,Nanjing Medical University,Nanjing 210029,China)

机构地区：[1]南京医科大学口腔疾病研究江苏省重点实验室,南京医科大学附属口腔医院综合科,江苏南京210029 [2]北京大清生物技术有限公司,北京100085

出　　处：《口腔医学》2019年第11期1017-1021,共5页Stomatology

基　　金：国家自然科学基金(81801029);江苏高校优势学科建设工程资助项目(2018-87)

摘　　要：目的研究在诊室漂白治疗前,不同方式使用生物活性玻璃脱敏剂对患者牙齿漂白性敏感的发生率以及敏感程度的影响。方法45例患者根据生物活性玻璃脱敏剂使用方式随机分为A、B、C3组,每组15例。A组使用涂抹法,B组使用透明托盘,C组为空白对照组不使用脱敏剂。每例患者的6颗上前牙作为观察单位。分别对3组受试者在漂白治疗术后即刻、24 h、48 h采用视觉模拟疼痛量表(VAS)进行牙齿敏感性的评估,对各组患者漂白治疗后牙齿敏感的发生率以及敏感程度进行统计学分析。结果术后即刻实验A组33.33%的患者和实验B组13.33%的患者出现了漂白性敏感症状,VAS评分的平均值分别为0.33±0.49、0.13±0.35,而对照组C组有86.67%患者出现漂白性敏感症状,VAS评分的平均值为1.53±0.82,术后即刻A、B两组与C组VAS平均值及敏感发生率均有统计学差异(P<0.05);术后24 h,敏感发生率A、B组均为0,C组为40%,A、B组的VAS平均值为0,C组的VAS平均值为0.47±0.63,A、B两组与C组的VAS平均值和敏感发生率均有统计学差异(P<0.05);术后48 h,AB组的敏感发生率均为0,C组敏感发生率为6.67%,C组的VAS平均值为0.07±0.25,3组的VAS平均值以及敏感发生率无差异(P>0.05)。结论生物活性玻璃脱敏剂以及透明托盘的使用可以显著减轻患者诊室漂白治疗术后的敏感症状,降低牙齿敏感的发生率。Objective To compare the effects of different treatment methods before in-office bleaching to investigate the occurrence rate and level of teeth bleaching sensitivity with bioactive glasses(BGs)application.Methods Forty-five subjects were randomized into 3 groups.In group A,all subjects were applied with BGs desensitizer.In group B,all subjects were applied with transparent tray and BGs desensitizer.Group C was the control group,without any desensitizer application.In every subject,the conditions of 6 front teeth were observed.Desensitizer applications were used in group A and B,while no desensitizer treatment in group C.Sensitivity scores(recorded on a 10-point visual-analog scale(VAS))were determined right after,24 h,48 h after the bleaching treatment in group A,B and C.The data of occurrence rate and level of teeth bleaching sensitivity with BSG application were analyzed and compared statistically.Results Bleaching sensitivity occurred in 33.33%of the subjects in Group A(right after)and 13.33%of the subjects in Group B(VAS mean scores:0.33±0.49,0.13±0.35).Bleaching sensitivity occurred in 86.67%of the subjects in Group C(right after)(VAS score:1.53±0.82).There were significant statistical differences between VAS mean values of A,B and C right after group(P<0.05).Twenty-four hours after treatment,bleaching sensitivity occurred in 0%of the subjects in Group A and B,and 40%of the subjects in Group C(VAS score:0.47±0.63).There were significant statistical differences between VAS mean values of A,B and C 24 h group(P<0.05).Forty-eight hours after treatment,bleaching sensitivity occurred in 0%of the subjects in Group A and B,and 6.67%of the subjects in Group C(VAS score:0.07±0.25).Bleaching sensitivity occurred in 86.67%of the subjects in Group C(right after)(VAS score:1.53±0.82).There were no significant statistical differences between VAS mean values of A,B and C 48 h group(P>0.05).Conclusion The application of BGs and transparent tray desensitizer may significantly reduce the occurrence rate of bleaching se

关 键 词：诊室漂白 生物活性玻璃脱敏剂 透明托盘 

分 类 号：R783.1[医药卫生—口腔医学]