肾动态显像在评价单侧肾积水患者肾功能的临床应用价值  

The clinical application value of renal dynamic imaging for renal function evaluation in patients with unilateral hydronephrosis

作　　者：张晶 钞卫光 吴宇平 胡光 陆克义 Zhang Jing;Chao Weiguang;Wu Yuping;Hu Guang;Lu Keyi(Department of Nuclear Medicine,the First Hospital of Shanxi Medical University,Molecular Imaging Precision Medicine Collaborative Innovation Center of Shanxi Medical University,Taiyuan 030001,China)

机构地区：[1]山西医科大学第一医院核医学科,山西医科大学分子影像精准诊疗协同创新中心,太原030001 [2]随州市中心医院核医学科

出　　处：《实用医学影像杂志》2019年第5期433-435,共3页Journal of Practical Medical Imaging

基　　金：山西省自然科学基金（201601D011097）;山西省高等学校科技创新项目（YG1502）

摘　　要：目的探讨二乙三胺五乙酸(^99mTc-DTPA)肾动态显像在评价单侧肾积水患者肾功能的临床应用价值。方法收集2017年12月至2018年8月我院治疗的单侧肾积水患者63例,依据肾积水程度将患者分为轻度积水组(18例)、中度积水组(19例)、重度积水组(26例)3组,选择健康成人20例作为对照组,所有研究对象均通过肾动态显像和双血浆法测定肾小球率过滤(GFR),分别记为g-GFR和d-GFR。结果与对照组健侧肾g-GFR相比:不同程度积水患者的患侧肾GRF均减低(P<0.05),且肾功能损伤程度为重度积水组>中度积水组>轻度积水组;在轻度、中度积水患者中g-GFR和d-GFR相关性较高(r=0.802、r=0.697,P<0.001、P=0.001)。结论99mTc-DTPA肾动态显像在不同程度单侧肾积水患者分肾功能评价中具有优势,并且在评估轻中度单侧肾积水患者的总肾功能时更敏感。Objective To investigate the clinical application value of renal dynamic imaging for renal function evaluatio in patients unilateral hydronephrosis.Methods Sixty-three patients with hydronephrosis were enrolled from December 2017 to August 2018,then divided into three groups,which were mild-group(n=18),moderate-group(n=19)and severe-group(n=26),according to degree of unilateral hydronephrosis,and 20 healthy subjects were enrolled at same time as control group.All of the subjects were calculated glomerular filtration rate(GFR)by renal dynamic imaging and two-sample method which were recorded as g-GFR and d-GFR.Results Comparison of g-GFR with healthy kidney in control group:the GRF of the affected kidney was decreased in patients with different degrees of hydronephrosis(P<0.05),among them,severe-group>moderate-group>mild-group.There was a high correlation between g-GFR and d-GFR in patients with mild and moderate hydronephrosis(r=0.802、r=0.697,P<0.001、P=0.001).Conclusion 99mTc-DTPA Renal dynamic imaging has advantages in evaluating unilateral renal function in patients with hydronephrosis and is more sensitive in evaluating total renal function in mild to moderate hydronephrosis.

关 键 词：肾盂积水 诊断显像 肾功能不全 

分 类 号：R[医药卫生]