喉炎症性肌纤维母细胞瘤一例  

A case of laryngeal inflammatory myofibroblastic tumor

作　　者：张贵鹏 王佩华 徐洲 普玉平[1,2] 史向娟 鲁建仑 

机构地区：[1]云南省大理州祥云县人民医院耳鼻咽喉科,云南大理672100 [2]上海交通大学附属第九人民医院耳鼻咽喉科,上海200011

出　　处：《中国医学文摘（耳鼻咽喉科学）》2019年第5期386-387,I0003,共3页Chinese Medical Digest(Otorhinolaryngology)

摘　　要：目的通过1例喉炎症性肌纤维母细胞瘤(Inflammatory myofibroblastic tumor,IMT)的临床特点、影像学表现、病理诊断及治疗方法,提高对本病的认识。方法回顾性分析1例喉IMT的病例资料,总结其临床特征,同时结合相关报道进行文献复习。结果喉IMT 1例临床主要表现为持续性进行性声嘶;CT表现为结节状软组织不均匀密度影;MRI表现为不规则结节状稍长T1、长T2信号影;病理检查梭形细胞为主要成分,免疫组化反应CD68、Ki-67、SMA呈阳性反应;手术方式选择开放入路喉裂开彻底切除。结论喉IMT临床及影像学表现无特异性,病理检查是诊断的金标准,手术是确切的治疗方法,术后无需放化疗,长期追踪随访是关键。Objective To improve the understanding of inflammatory myofibroblastic tumor(IMT), a case study was conducted by the method of clinical features, imaging findings, pathological diagnosis and corresponding treatment. Methods A case of laryngeal IMT was retrospectively analyzed, and its clinical features were summarized. Literature review was also carried out in combination with relevant reports. Results One case of laryngeal IMT was mainly characterized by persistent progressive hoarseness;CT showed nodular soft tissue uneven density;MRI showed irregular nodular slightly long T1 and T2 signal;pathological examination showed fusiform cells were the main components, and the immunohistochemical reactions were positive for CD68, Ki-67, and SMA. The surgical approach was to open the laryngeal split and completely resected. Conclusions The clinical and imaging findings of laryngeal IMT are non-specific. Pathological examination is the gold standard for diagnosis. Surgery is the exact treatment. There is no need for radiotherapy and chemotherapy after operation. Long-term follow-up is the key.

关 键 词：炎症性肌纤维母细胞瘤 喉 

分 类 号：R73[医药卫生—肿瘤]