内镜下治疗7例食管颗粒细胞瘤临床报道  

Clinical report of 7 cases of esophageal granular cell tumors by endoscopic treatment

作　　者：花海洋 蒋海森[3] 李建辉[2] 孙秀静[1] HUA Haiyang;JIANG Haisen;LI Jianhui;SUN Xiujing(Department of Gastroenterology,Affiliated Beijing Friendship Hospital,Capital Medical University/National Clinical Research Center for Digestive Diseases/Beijing Municipal Digestive Disease Center/Gastroenterology Faculty of Capital Medical University/Beijing Key Laboratory for Precancerous Lesion of Digestive Diseases,Beijing 100050,China;Department of Gastroenterology,Chengde Municipal Central Hospital,Chengde,Hebei 067000,China;Department of Geriatrics,Affiliated Hospital of Chengde Medical College,Chengde,Hebei 067000,China)

机构地区：[1]首都医科大学附属北京友谊医院消化内科/国家消化系统疾病临床医学研究中心/北京市消化疾病中心/首都医科大学消化病学系/消化疾病癌前病变北京市重点实验室,北京100050 [2]河北省承德市中心医院消化内科,067000 [3]承德医学院附属医院老年病科,河北承德067000

出　　处：《重庆医学》2019年第22期3845-3847,共3页Chongqing medicine

摘　　要：目的探讨食管颗粒细胞瘤的临床表现、内镜特点、治疗及预后。方法回顾性分析2009年1月至2018年4月于首都医科大学附属北京友谊医院诊治且资料完整的食管颗粒细胞瘤患者的临床表现、白光内镜及超声内镜特点并复习相关文献。结果共纳入7例患者,其中男3例,女4例,年龄35~57岁,平均(47.8±7.9)岁,肿物直径0.2~1.1 cm。7例患者术前均行超声内镜检查,随后行内镜下切除术,术后病理免疫组织化学S-100、CD68、Vimentin阳性,证实为食管颗粒细胞瘤。结论超声内镜对于确定病变的起源浸润层次有一定指导意义,确诊仍需病理形态学及免疫组织化学,内镜下黏膜剥离术是目前较为安全可靠的方法。Objective To explore the clinical manifestations,endoscopic features,treatment and prognosis of esophageal granular cell tumor.Methods The clinical manifestations,white light endoscopic and ultrasound endoscopic features in the patients with esophageal granular cell tumor and intact data diagnosed and treated in the Affiliated Beijing Friendship Hospital of Capital Medical University from January 2009 to April 2018 were retrospectively analyzed and the related literatures were reviewed.Results Totally 7 cases were included,3 males and 4 females,the age was 35-57 years old with an average age of(47.8±7.9)years old.The tumor size ranged 0.2-1.1 cm.All 7 cases conducted endoscopic ultrasonographic examination before operation and then performed endoscopic resection.The postoperative pathological immunohistochemical results showed positive for S-100,CD68 and Vimentin,and esophageal granular cell tumor was verified.Conclusion Ultrasonographic endoscopy has a certain guiding significance for determining the origin and invasion layers of lesions.The definite diagnosis still needs the pathomorphology and immunohistochemistry.The endoscopic mucosal resection is a safe and reliable therapeutic method at present.

关 键 词：食管颗粒细胞瘤 临床特点 内镜表现 病理特征 内镜治疗 

分 类 号：R735.1[医药卫生—肿瘤]