阿司匹林联合依达拉奉治疗急性脑梗死的效果及对炎症因子水平的影响  

Effect of aspirin combined with edaravone on acute cerebral infarction and its influence on the level of inflammatory factors

作　　者：刘小丽[1] 高咏梅[1] LIU Xiao-li;GAO Yong-mei(Hancheng People's Hospital,Hancheng 715400,China)

机构地区：[1]韩城市人民医院

出　　处：《临床医学研究与实践》2019年第34期48-49,共2页Clinical Research and Practice

摘　　要：目的探讨阿司匹林联合依达拉奉治疗急性脑梗死的效果及对炎症因子水平的影响。方法将我院收治的60例急性脑梗死患者依据随机数字表法分为对照组(30例,阿司匹林)和观察组(30例,阿司匹林+依达拉奉)。比较两组患者的临床疗效。结果观察组的治疗总有效率明显高于对照组(P<0.05)。治疗后,两组的NIHSS评分、CRP、IL-6水平均低于治疗前,且观察组明显低于对照组(P<0.05)。结论阿司匹林联合依达拉奉治疗急性脑梗死的效果显著,可有效改善患者的神经功能,抑制炎症因子活性,且安全性较高。Objective To investigate the effect of aspirin combined with edaravone on acute cerebral infarction and its influence on the level of inflammatory factors. Methods A total of 60 patients with acute cerebral infarction admitted in our hospital were divided into control group(30 cases, aspirin) and observation group(30 cases, aspirin+edaravone) according to the random number table method. The clinical efficacy was compared between the two groups. Results The total effective rate of treatment in the observation group was significantly higher than that in the control group(P<0.05). After treatment,the NIHSS score, the levels of CRP and IL-6 in the two groups were lower than those before treatment, and those in the observation group were significantly lower than the control group(P<0.05). Conclusion Aspirin combined with edaravone on acute cerebral infarction has a significant effect, which can effectively improve the neurological function of patients,inhibit the activity of inflammatory factors, and has high safety.

关 键 词：急性脑梗死 阿司匹林 依达拉奉 

分 类 号：R743[医药卫生—神经病学与精神病学]