精神分裂症与双相情感障碍的认知功能对比分析  

A comparative study of cognitive function between schizophrenia and bipolar disorder

作　　者：林凯[1] 徐国正[1] Lin Kai;Xu Guozheng(Urumqi No.4 People's Hospital,Urumqi,Xinjiang 830000,China)

机构地区：[1]乌鲁木齐市第四人民医院,新疆乌鲁木齐830000

出　　处：《医药前沿》2019年第32期26-27,共2页Journal of Frontiers of Medicine

摘　　要：目的:探讨比较精神分裂症与双向情感障碍的认知功能.方法:选择2017年2月—2019年2月我院收治的精神分裂与双相情感障碍患者各60例分为对照组和观察组,其中60例双向情感障碍患者为观察组,其余60例精神分裂症患者为对照组,经过治疗后,比较两组患者的认知功能损害程度以及治疗后阳性与阴性症状量表(PANSS)评分,对所有人进行认知心理测验.结果:两组治疗前认知功能损害程度无统计学意义(P>0.05);经治疗后,观察组患者的数字符号、视觉再生、数字广度倒背评分高于对照组(P<0.05);WCST分类个数多于对照组(P<0.05),错误数、连续错误数少于对照组(P<0.05);两组患者的数字广度顺背、连线测试A、B评分之间的差异无统计学意义(P>0.05);治疗后,观察组患者的一般精神、阳性、阴性症状评分以及总分低于对照组(P<0.05).结论:经过治疗后,双向情感障碍患者的认知功能损害程度较精神分裂患者低,双向情感认知障碍患者的认知功能比精神分裂患者要恢复的好.Objective To explore the cognitive function comparison between Schizophrenia and Bipolar affective disorder.Methods 120 patients from February 2017 to February 2019 were selected and divided into control group and observation group,of which 60 patients with bi-directional affective disorder were the observation group and the other 60 patients with schizophrenia were the control group.After treatment,the cognitive function damage degree,positive and negative symptom scale(PANSS)scores before and after treatment were compared between the two groups,and cognitive psychological tests were conducted on all patients.Results There was no significant difference in the degree of cognitive impairment before treatment between the two groups(P>0.05).After treatment,the scores of digital symbols,visual regeneration and digital breadth inversion in the observation group were higher than those in the control group(P<0.05).The number of WCST classifications was more than that of the control group(P<0.05),and the number of errors and consecutive errors were less than that of the control group(P<0.05).There was no significant difference between the two groups(P>0.05).After treatment,the general mental,positive and negative symptom scores and total scores of patients in the observation group were lower than those in the control group(P<0.05).Conclusion After treatment,the degree of cognitive impairment of patients with bipolar affective disorder is lower than that of schizophrenic patients,and the cognitive function of patients with bipolar affective cognitive disorder is better than that of schizophrenic patients.

关 键 词：精神分裂 双向情感障碍 认知功能对比 阳性与阴性症状量表 

分 类 号：R743.05[医药卫生—神经病学与精神病学]