改良中药离子导入疗法治疗非酒精性脂肪性肝病的临床效果  

Clinical efficacy of modified Chinese medicine iontophoresis in the treatment of nonalcoholic fatty liver disease

作　　者：阴霄飞 孙岷[1] 李惠玲 卢根娣[1] YIN Xiaofei;SUN Min;LI Huiling;LU Gendi(Traditional Medical Rehabilitation Treatment Center,Shuguang Hospital Affiliated to Shanghai University of Traditional Chinese Medicine,Shanghai201203,China)

机构地区：[1]上海中医药大学附属曙光医院传统医学康复治疗中心

出　　处：《中国医药导报》2019年第31期115-118,共4页China Medical Herald

基　　金：上海卫生计生系统重要薄弱学科(中医护理学建设项目(2015ZB0306)

摘　　要：目的探讨改良中药离子导入疗法对非酒精性脂肪性肝病患者的影响。方法选择2017年7月~2018年5月就诊于上海中医药大学附属曙光医院肝病科门诊的非酒精性脂肪性肝病患者72例,按照随机数字表法分为对照组和观察组,每组各36例。对照组在常规治疗基础上采用常规中药离子导入疗法,观察组采用改良中药离子导入疗法。比较两组的体重指数(BMI)、中医证候积分、血浆总胆固醇、高密度脂蛋白、低密度脂蛋白、三酰甘油水平,以及肝脏受控衰减参数(CAP)值。结果两组治疗后的BMI和中医证候积分均较治疗前明显降低(P <0.05),但治疗后组间差异无统计学意义(P> 0.05)。两组治疗后的总胆固醇、低密度脂蛋白及三酰甘油水平均较治疗前明显降低(P <0.05),高密度脂蛋白较治疗前明显升高(P <0.05)。观察组治疗后的三酰甘油低于对照组,差异有统计学意义(P <0.05);两组治疗后的总胆固醇、高密度脂蛋白、低密度脂蛋白水平比较差异无统计学意义(P> 0.05)。两组治疗后的肝脏CAP值均较治疗前明显降低,且观察组明显低于对照组,差异有统计学意义(P <0.05)。结论改良中药离子导入疗法能提高非酒精性脂肪性肝病的疗效,具有推广价值。Objective To investigate the effect of modified Chinese medicine iontophoresis on patients with nonalcoholic fatty liver disease. Methods Seventy-two patients with nonalcoholic fatty liver disease were selected from July2017 to May 2018 in Department of Liver Disease, Shuguang Hospital Affiliated to Shanghai University of Traditional Chinese Medicine. According to the random number table method, they were randomly divided into control group and observation group, with 36 cases in each group. Control group was treated with conventional Chinese medicine iontophoresis on the basis of conventional treatment, while observation group was treated with improved Chinese medicine iontophoresis. Body mass index(BMI), traditional Chinese medicine syndrome integral, plasma total cholesterol, highdensity lipoprotein, low-density lipoprotein, triglyceride levels and CAP value were compared between two groups. Results BMI and traditional Chinese medicine syndrome scores of two groups after treatment were significantly lower than before treatment(P < 0.05), but there was no significant difference between two groups after treatment(P > 0.05). The levels of total cholesterol, low-density lipoprotein and triglyceride in two groups were significantly lower than those before treatment(P < 0.05), and high-density lipoprotein was significantly higher than before treatment(P < 0.05).Triglyceride in observation group was lower than that in control group after treatment, the difference was statistically significant(P < 0.05). There was no significant difference in the levels of total cholesterol, high-density lipoprotein and low-density lipoprotein between two groups after treatment(P > 0.05). The CAP value of liver in two groups after treatment was significantly lower than that before treatment, observation group was significantly lower than control group,and the differences were statistically significant(P < 0.05). Conclusion Modified Chinese medicine iontophoresis can improve the curative effect of nonalcoholic fatty liver disease, and

关 键 词：非酒精性脂肪性肝病 中医护理技术 改良中药离子导入 肝脏受控衰减参数 

分 类 号：R575[医药卫生—消化系统]