同步放化疗与序贯放化疗治疗局部晚期非小细胞肺癌的效果比较  

Comparison of the effect of concurrent and sequential radiotherapy and chemotherapy in the treatment of locally advanced non-small cell lung cancer

作　　者：俞峰[1] 张利 瞿凯泉 Yu Feng;Zhang Li;Qu Kaiquan(The People's Hospital of Qidong City,226200)

机构地区：[1]启东市人民医院

出　　处：《中国社区医师》2019年第34期78-79,共2页Chinese Community Doctors

摘　　要：目的:观察同步放化疗及序贯放化疗治疗局部晚期非小细胞肺癌的效果。方法:2014年5月-2016年1月收治局部晚期非小细胞肺癌患者74例,随机分为两组各37例。两组均接受DP方案进行化疗,对比组实施序贯放化疗,观察组实施同步放化疗。比较两组效果。结果:观察组临床总有效率明显高于对比组,差异有统计学意义(P<0.05)。观察组感染、脱发、白细胞减少及胃肠道反应等不良反应发生率低于对比组,差异有统计学意义(P<0.05)。结论:局部晚期非小细胞肺癌患者采用同步放化疗病情控制效果更加理想,且治疗安全性更高。Objective:To contrast the effect of concurrent and sequential radiotherapy and chemotherapy in the treatment of locally advanced non-small cell lung cancer.Methods:From May 2014 to January 2016,74 patients with locally advanced non-small cell lung cancer were selected and randomly divided into two groups of 37 cases in each.Both groups received chemotherapy with DP regimen,the control group received sequential radiotherapy and chemotherapy,and the observation group received concurrent radiotherapy and chemotherapy,we compared the effect of the two groups.Results:In the observation group,the total clinical effective rate was significantly higher than the control group,the difference was statistically significant(P<0.05).In the observation group,the incidence of infection,alopecia,leukopenia and gastrointestinal reaction was lower than that in the control group,the difference was statistically significant(P<0.05).Conclusion:It was more ideal and safe to use concurrent radiotherapy and chemotherapy in patients with locally advanced non-small cell lung cancer.

关 键 词：同步放化疗 序贯放化疗 局部晚期非小细胞肺癌 

分 类 号：R73[医药卫生—肿瘤]