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作 者:张梅 ZHANG Mei(Department of Radiation Oncology,The Third Hospital of Nanjing,Nanjing Jiangsu 210003,China)
机构地区:[1]江苏省南京市第三医院放疗科
出 处:《中国继续医学教育》2019年第34期141-143,共3页China Continuing Medical Education
摘 要:目的观察三乙醇胺乳膏加米汤保留灌肠法预防经盆腔放疗后发生放射性肠炎的疗效。方法选取本院放疗科2016年1月-2018年12月行盆腔放疗的恶性肿瘤患者共80例,按照入院先后顺序随机均分为两组,其中对照组40例,观察组40例。对照组给予放疗常规护理指导、预防性口服药物治疗及不予保留灌肠护理措施,观察组在对照组基础上采用三乙醇胺乳膏加米汤行保留灌肠干预措施。干预周期从放疗第一天开始,连续灌至放疗结束。对比两组患者放射性肠炎发生时间、发生率及程度分级,以及放疗前后血象及白蛋白生化指标的变化。结果观察组于放疗第3周起发生急性放射性肠炎,对照组于放疗第2周起发生急性放射性肠炎,观察组放射性肠炎发生率为7.5%,对照组放射性肠炎发生率为35.0%,观察组与对照组相比发生急性放射性肠炎及慢性放射性肠炎比率明显降低,发生时间也晚于对照组;观察组放疗前后血象及白细胞下降情况明显低于对照组,以上差异均有统计学意义(P <0.05)。结论三乙醇胺乳膏加米汤保留灌肠能明显延迟盆腔放疗患者放射性肠炎发生时间,降低放射性肠炎发生率,对患者的血象及白蛋白影响程度也明显降低,有利于症状改善及病情发展的控制。Objective To observe the effect of triethanolamine cream plus rice soup retention enema to prevent radiation enteritis after pelvic radiotherapy. Methods A total of 80 patients with malignant tumors who underwent pelvic radiotherapy from January 2016 to December 2018 in our hospital were randomly divided into two groups according to the order of admission, including 40 in the control group and 40 in the observation group. The control group received radiotherapy routine nursing guidance, preventive oral medication and no retention enema nursing measures. The observation group used triethanolamine cream plus rice soup to preserve enema intervention on the basis of the control group. The intervention cycle begins on the first day of radiotherapy and continues until the end of radiotherapy. The time, incidence and extent of radiation enteritis were compared between the two groups, and the changes of blood and albumin biochemical indicators before and after radiotherapy. Results In the observation group, acute radiation enteritis occurred in the third week of radiotherapy. In the control group, acute radiation enteritis occurred in the second week of radiotherapy. The incidence of radiation enteritis in the observation group was 7.5%, and the incidence of radiation enteritis in the control group was 35.0%. Compared with the control group, the ratio of acute radiation enteritis and chronic radiation enteritis was significantly lower than that of the control group. The hemogram and leukocyte decline of the observation group before and after radiotherapy was significantly lower than that of the control group. The above differences were statistically significant(P<0.05). Conclusion Triethanolamine cream and rice soup retention enema can significantly delay the occurrence of radiation enteritis in patients with pelvic radiotherapy, reduce the incidence of radiation enteritis, and significantly reduce the impact of blood and albumin on patients, which is conducive to the improvement of symptoms and the development of diseas
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