药盐包联合艾灸防治乳腺癌化疗所致不良反应的临床研究  

Clinical Study on Medicated Salt packet Combined with Moxibustion in Prevention of Adverse Reactions Caused by Chemotherapy for Breast Cancer

作　　者：张蕾[1] 周江红[1] 祁海燕[1] 李艳芳[1] 薛婧婧 ZHANG Lei;ZHOU Jiang-hong;QI Hai-yan(Gansu Cancer Hospital,Lanzhou,730050,China)

机构地区：[1]甘肃省肿瘤医院

出　　处：《中国初级卫生保健》2019年第11期109-111,119,共4页Chinese Primary Health Care

基　　金：甘肃省卫生行业科研计划项(20180518s)

摘　　要：目的分析药盐包联合艾灸用于防治乳腺癌患者化疗期间不良反应的价值。方法选取2018年3月—2019年6月在甘肃省肿瘤医院接受化疗的120例乳腺癌患者为研究对象,按照随机数字表法分为对照组、实验1组和实验2组,每组各40例,所有患者化疗方案均为FEC一线化疗方案。对照组在化疗开始前30 min静脉推注注射用盐酸托烷司琼,实验1组在对照组基础上在化疗前30 min联合实施逆降止呕电加热药盐包热敷中脘穴+艾灸双侧足三里、内关穴,实验2组在对照组基础上在化疗前30 min、化疗结束后30 min分别实施逆降止呕电加热药盐包热敷中脘穴+艾灸双侧足三里、内关穴。化疗结束后,比较三组患者住院治疗时间、住院治疗费用、恶心呕吐程度、腹胀程度和食欲情况。结果实验2组恶心呕吐、腹胀程度最轻微,食欲最佳,其次为实验1组,对照组恶心呕吐、腹胀程度相对严重,食欲不佳,实验1组、实验2组分别与对照组比较,差异均有统计学意义(P<0.05);实验2组恶心呕吐、腹胀程度较实验1组轻微,食欲较实验1组好,但组间比较差异无统计学意义(P>0.05);实验2组住院治疗时间最短、住院治疗花费最少,其次为实验1组、对照组,组间两两比较差异有统计学意义(P<0.05)。结论化疗前后药盐包联合艾灸用于乳腺癌化疗所致不良反应的防治,有利于减轻患者化疗期间的胃肠道反应,减轻腹胀程度,明显提升食欲,这对增加化疗安全性、增强化疗效果和提高患者生活质量具有重要意义,值得推广应用。OBJECTIVE To analyze the value of medicated salt packet combined with moxibustion in prevention of adverse reactions caused by chemotherapy for breast cancer.METHODS 120 breast cancer patients with chemotherapy in the hospital from March 2018 to June 2019 were divided into control group,experimental 1 group and experimental 2 group by random number table,with 40 cases in each group.All patients were given FEC first-line chemotherapy regimen.Control group was given intravenous injection of granisetron hydro chloride before chemotherapy for 30 min.Experimental 1 group was given electrical heating medicated salt packet in Zhongwan point+moxibustion in bilateral Zusanli point and Neiguan point before chemotherapy for 30min based on control group.Experimental 2 group was given electrical heating medicated salt packet in Zhongwan point+moxibustion in bilateral Zusanli point and Neiguan point before chemo therapy for 30 min and after chemotherapy for 30 min based on control group.After chemotherapy,the hospital stays,hospitalization ex pense,degree of nausea and vomiting,degree of abdominal distension,appetite were compared among three groups.RESULTS The de gree of nausea and vomiting,abdominal distension in experimental 2 group was the slightest,and the appetite of experimental 2 group was the best,followed by experimental 1 group,the degree of nausea and vomiting and abdominal distension in control group was rela tively severe,and there was statistical difference among experimental 1 group,experimental 2 group and control group(P<0.05).The degree of nausea and vomiting,abdominal distension in experimental 2 group was slighter than that in experimental 1 group,the appe tite of experimental 2 group was better than experimental 1 group,but there was no statistical difference between these two groups(P>0.05);the hospital stays in experimental 2 group were the shortest,and the hospitalization expense of experimental 2 group was the least,followed by experimental 1 group and control group,and the difference was statisticall

关 键 词：乳腺癌 化疗 药盐包 艾灸 不良反应 

分 类 号：R737.9[医药卫生—肿瘤]