多参数磁共振成像在前列腺癌中的诊断价值  

Diagnostic value of multi-parameter magnetic resonance imaging in prostate cancer

作　　者：王立鹏[1] 阳青松[1] 张威[2] 王振[1] 陈玉坤 陆建平[1] WANG Li-peng;YANG Qing-song;ZHANG Wei;WANG Zhen;CHEN Yu-kun;LU Jian-ping(Department of Radiology,Changhai Hospital,Naval Medical University(Second Military Medical University),Shanghai 200433,China;Department of Urology,Changhai Hospital,Naval Medical University(Second Military Medical University),Shanghai 200433,China)

机构地区：[1]海军军医大学(第二军医大学)长海医院影像医学科,上海200433 [2]海军军医大学(第二军医大学)长海医院泌尿外科,上海200433

出　　处：《第二军医大学学报》2019年第11期1236-1241,共6页Academic Journal of Second Military Medical University

基　　金：国家自然科学基金(81802581)~~

摘　　要：前列腺癌(PCa)是全球范围内发病率最高的男性恶性肿瘤之一,严重危害着老年男性的身心健康,早期诊断和早期治疗对PCa治疗策略的制定和预后的判断非常关键。目前PCa诊断主要依靠直肠指诊、血清前列腺特异性抗原及经直肠超声引导下穿刺活组织检查。但这些方法的诊断效能均较低。近年来随着功能磁共振成像的推广运用,多参数磁共振成像(mpMRI)成为目前公认的诊断PCa最有效的影像学方法,其不仅能够进行前列腺疾病的鉴别诊断,还能进一步预测PCa病理评分,以及指导后续的靶向穿刺及局部治疗。mpMRI对PCa的精确诊断和后续的个体化治疗意义重大,本文就其在PCa诊断中的研究现状作一综述。Prostate cancer is one of the male malignancies with the highest incidence rate in the world, which seriously endangers the physical and mental health of elderly men. Early diagnosis and treatment are critical for the formulation of treatment strategies and the prognosis of prostate cancer. At present, its diagnosis mainly depends on digital rectal examination, serum prostate-specific antigen and transrectal ultrasound guided biopsy. However, the diagnostic efficiency of these methods is very low. In recent years, with the introduction of functional magnetic resonance imaging, multi-parameter magnetic resonance imaging(mpMRI) is currently recognized as the most effective imaging method for diagnosing prostate cancer. Besides the differential diagnosis of prostate diseases, it could further predict the pathological score of prostate cancer and guide the subsequent targeted biopsy and local treatment. Accurate diagnosis of prostate cancer and subsequent individualized treatment are of great significance. The current status of mpMRI in the diagnosis of prostate cancer is reviewed in this paper.

关 键 词：多参数磁共振成像 前列腺肿瘤 诊断 磁共振成像 

分 类 号：R737.25[医药卫生—肿瘤]