子宫肌瘤HIFU术后骶骨MR异常信号的影响因素研究  

The influencing factors of sacrum abnormal MR signal occurring after HIFU for uterine fibroids

作　　者：张雅姣 肖智博[1] 吕富荣[1] 刘梓菀 黄浩然[2] ZHANG Yajiao;XIAO Zhibo;LV Furong;LIU Ziyu;HUANG Haoran(Department of Radiology,First Affiliated Hospital of Chongqing Medical University,Chongqing 400016,China)

机构地区：[1]重庆医科大学附属第一医院放射科,400016 [2]重庆医科大学附属第一医院超声医疗国家工程研究中心,400016

出　　处：《介入放射学杂志》2019年第11期1066-1070,共5页Journal of Interventional Radiology

基　　金：重庆市卫生计生委医学科研计划面上项目（2017MSXM022）

摘　　要：目的探讨子宫肌瘤高强度聚焦超声(HIFU)消融术后骶骨MR异常信号的影响因素。方法回顾性分析2017年3月-2018年8月初次行HIFU治疗的133例子宫肌瘤患者的盆腔MRI及临床资料,记录子宫肌瘤特征及HIFU治疗参数。结果 36例(27.1%)患者在HIFU术后MRI观察到骶骨异常信号。单因素分析中,骶骨MR异常信号与肌瘤骶骨距离、HIFU治疗总能量和辐照时间相关(P均<0.05)。多因素logistic回归分析中,肌瘤骶骨距离差异有统计学意义(P=0.003),OR值为0.918,95%CI 0.868~0.971。结论肌瘤骶骨距离、HIFU辐照时间及治疗总能量与骶骨MR异常信号的出现密切相关,且肌瘤骶骨距离是骶骨MR异常信号的保护因素。Objective To investigate the influencing factors of sacrum abnormal magnetic resonance(MR) signal occurring after high-intensity focused ultrasound(HIFU) ablation for uterine fibroids. Methods The clinical data and pelvic MRI materials of 133 patients with uterine fibroids, who received initial HIFU ablation during the period from March 2017 to August 2018, were retrospectively analyzed. The features of uterine fibroids and therapeutic parameters of HIFU were analyzed. Results In 36 patients(27.1%), sacrum abnormal MR signal was observed after HIFU. Univariate analysis indicated that sacrum abnormal MR signal was significantly correlated with the fibroid-sacral distance, the total therapeutic energy and irradiation time of HIFU treatment(P<0.05). Multivariate logistic regression analysis revealed that the difference in fibroid-sacral distance was statistically significant(P=0.003). The OR value was 0.918, and 95%CI value was 0.868-0.971.Conclusion A significant correlation exists between the fibroid-sacral distance, the irradiation time of HIFU,the total therapeutic energy and the occurrence of sacrum abnormal MR signal. The fibroid-sacral distance is a protective factor for sacrum abnormal MR signal.

关 键 词：高强度聚焦超声 子宫肌瘤 骶骨 MRI 

分 类 号：R737.33[医药卫生—肿瘤]