ABO血型与卵巢透明细胞癌的关系研究  

Relationship between ABO blood type and ovarian clear cell carcinoma

作　　者：汪洋[1] 何灿 杨静[1] 蔡红兵[1] WANG Yang;HE Can;YANG Jing;CAI Hongbing(Department of Gynecological Oncology,Zhongnan Hospital of Wuhan University,Hubei Cancer Clinical Study Center,Hubei Key laboratory of Tumor Biological Behaviors,Hubei,Wuhan 430071,China)

机构地区：[1]武汉大学中南医院妇瘤科/湖北省肿瘤医学研究中心/肿瘤生物学行为湖北省重点实验室,湖北武汉430071

出　　处：《检验医学与临床》2019年第S02期89-92,共4页Laboratory Medicine and Clinic

摘　　要：目的探讨血型与卵巢透明细胞癌患者临床特征及预后之间的关系。方法回顾性分析52例透明细胞癌患者的临床资料,将患者分为A+和A-两组,用卡方检验比较两组患者的临床病理特征分布,采用Kaplan-Meier绘制生存曲线,并对各个病理特征进行分层分析,Log-rank法比较两组血型患者间生存率的差异。结果两组血型患者间的临床病理特征分布差异无统计学意义(P>0.05)。生存曲线发现两组血型患者的总生存期及无进展生存期间的差异均无统计学意义(P>0.05)。分层分析发现在Ⅰ~Ⅱ期亚组中,A+型血患者的总生存率及无进展生存率均较A-患者好(P<0.05),但在Ⅲ~Ⅳ期或存在残余瘤的亚组中,A+血型患者的生存率均较A-血型患者差(P<0.05)。结论血型与卵巢透明细胞癌患者的临床特征无明显关系,当患者处于Ⅰ~Ⅱ期时,A+血型的患者预后较好,Ⅲ~Ⅳ期或存在残余瘤时,A+血型患者的预后较差。Objective To investigate the relationship between blood type and clinical features and prognosis of patients with ovarian clear cell carcinoma.Methods The clinical data of 52 patients with clear cell carcinoma were retrospectively analyzed.The patients were divided into A+and A-groups.The clinicopathological features of the two groups were compared by chi-square test.The survival curves were drawn by Kaplan-Meier.The pathological features were analyzed by stratification,and the log-rank method was used to compare the difference in survival rate between the two groups.Results There was no difference in the distribution of clinicopathological features between the two groups(P>0.05).Survival curves showed no significant difference in the overall survival and progression-free survival between the two groups(P>0.05).In the stratified analysis,the prognosis of patients with A+blood was better than that of A-patients in theⅠ-Ⅱsubgroup(P<0.05),but in theⅢ-Ⅳor subgroup with residual tumors,A+The prognosis of patients with blood type was worse than that of patients with A-type(P<0.05).Conclusion There is no significant relationship between the blood type and the clinical features and prognosis of patients with ovarian clear cell carcinoma,but when the patient is in stage I-II,the prognosis of patients with A+blood type is better,and the prognosis of patients with A+blood type in stageⅢ-Ⅳor residual tumor is poorer.

关 键 词：血型 透明细胞癌 预后 

分 类 号：R73[医药卫生—肿瘤]