帕金森病合并冲动控制障碍研究进展  

Research progress of Pakinson disease with impulse control disorder

作　　者：唐晓梅[1] 张燕辉[1] 史冬梅[1] 冯浩[1] 王玮婧 孟晓梅[1] 余秋瑾 闫紫 Tang Xiaomei;Zhang Yanhui;Shi Dongmei;Feng Hao;Wang Weijing;Meng Xiaomei;Yu Qiujin;Yan Zi(Neurology Department,Beijing Haidian Hospital,Beijing 100080,China)

机构地区：[1]北京市海淀医院神经内科,100080

出　　处：《神经疾病与精神卫生》2019年第8期861-864,共4页Journal of Neuroscience and Mental Health

摘　　要：冲动控制障碍(ICD)是在帕金森病患者诊治过程中需要关注的并发症,在使用多巴胺受体激动剂治疗后ICD发生率明显增加.帕金森病患者合并ICD,可能机制为中脑-纹状体-边缘系统-皮质区的纤维联系改变.多巴胺能药物治疗、性别、吸烟、多巴胺转运体的减少与ICD的发生可能相关.现就帕金森病中的ICD相关研究作一综述.Impulse control disorder(ICD)is a complication in Pakinson disease requiring attention.There is a significant increase in the incidence of ICD after using dopamine agonists.In Parkinson disease patients with ICD,there are corresponding changes of fiber connections in the midbrain-striatum-limbic system-cortex.The occurrence of ICD in Parkinson disease is related to dopaminergic drug therapy,gender,smoking and the decrease of dopamine transporter.This review summarizes the relevant findings concerning ICD in Parkison disease.

关 键 词：帕金森病 冲动控制障碍 综述 

分 类 号：R74[医药卫生—神经病学与精神病学]