胸段食管癌喉返神经旁淋巴结转移的特点及发生情况分析  

Characteristics and Incidence of Paralaryngeal Lymph Node Metastasis in Thoracic Esophageal Cancer

作　　者：施我大[1] 高正亚[1] 王进[1] 戚建伟 刘星辰 王文才[1] SHI Woda;GAO Zhengya;WANG Jin(Third People's Hospital of Yancheng,Yancheng,224000)

机构地区：[1]江苏省盐城市第三人民医院

出　　处：《实用癌症杂志》2019年第12期1965-1968,共4页The Practical Journal of Cancer

摘　　要：目的探讨胸段食管癌喉返神经旁淋巴结转移特点及发生率。方法随机选取胸段食管癌患者80例,分析80例患者喉返神经旁淋巴结转移发生情况、影响因素,统计分析发生、喉返神经旁淋巴结转移患者颈部淋巴结转移发生情况、3年生存情况。结果80例患者中,发生喉返神经旁淋巴结转移30例,发生率为37.5%,其中11例在左侧,14例在右侧,5例在双侧。共检出350枚淋巴结,其中120枚为转移淋巴结。胸上段患者喉返神经旁淋巴结转移发生率显著高于胸中段、胸下段患者(P<0.05),但胸中段、胸下段患者喉返神经旁淋巴结转移发生率间差异不显著(P>0.05);低分化患者喉返神经旁淋巴结转移发生率显著高于中分化、高分化患者(P<0.05),中分化、高分化患者喉返神经旁淋巴结转移发生率间差异不显著(P>0.05);T3、T4患者喉返神经旁淋巴结转移发生率均显著高于T1、T2患者(P<0.05),T1、T2和T3、T4患者喉返神经旁淋巴结转移发生率的差异均不显著(P>0.05);有颈部淋巴结转移患者喉返神经旁淋巴结转移发生率显著高于无颈部淋巴结转移患者(P<0.05);不同性别、年龄患者喉返神经旁淋巴结转移发生率的差异均不显著(P>0.05)。发生喉返神经旁淋巴结转移患者颈部淋巴结转移发生率[66.7%(20/30)]显著高于未发生患者[30.0%(15/50)](P<0.05),3年生存率[40.0%(12/30)]显著低于未发生患者[76.0%(38/50)](P<0.05)。结论胸段食管癌喉返神经旁淋巴结转移的发生受到肿瘤部位、分化程度、浸润深度、颈部淋巴结转移的影响,提升了患者的颈部淋巴结转移发生率,降低了患者的3年生存率。Objective To investigate the characteristics and incidence of paralaryngeal lymph node metastasis in thoracic esophageal cancer.Methods 80 patients with thoracic esophageal cancer were randomly selected.The occurrence and influencing factors of lymph node metastasis of recurrent laryngeal nerve in 80 patients were analyzed.Statistical analysis of occurrence,cervical lymph node metastasis and 3-year survival of patients with recurrent laryngeal nerve lymph node metastasis.Results Of the 80 patients,30 cases had recurrent laryngeal nerve lymph node metastasis.The birth rate was 37.5%.11 cases were on the left side,14 cases on the right side and 5 cases on both sides.A total of 350 lymph nodes were detected.120 of them were metastatic lymph nodes.The incidence of lymph node metastasis in the upper thoracic segment was significantly higher than that of the middle and lower thoracic segments(P<0.05).However,there was no significant difference in the incidence of LN metastasis between the middle and lower thoracic segments(P>0.05).The incidence of LN metastasis in poorly differentiated patients was significantly higher than that of moderately differentiated and highly differentiated patients(P<0.05).There was no significant difference in the incidence of lymph node metastasis between moderately differentiated and highly differentiated patients(P>0.05).The incidence of LN metastasis in patients with T3 and T4 was significantly higher than that of patients with T1 and T2(P<0.05).There was no significant difference in the incidence of LN metastasis among T1,T2,T3 and T4 patients(P>0.05).The incidence of recurrent laryngeal nerve lymph node metastasis in patients with cervical lymph node metastasis was significantly higher than that of patients without cervical lymph node metastasis(P<0.05).There was no significant difference in the incidence of lymph node metastasis in recurrent laryngeal nerve between patients of different sex and age(P>0.05).The incidence of cervical lymph node metastasis in patients with recurrent lary

关 键 词：胸段食管癌 喉返神经旁 淋巴结转移 特点 发生率 

分 类 号：R735.1[医药卫生—肿瘤]