以脑出血为首发表现的妊娠滋养细胞肿瘤一例  

One Case of Gestational Trophoblastic Neoplasia with Cerebral Hemorrhage as the Primary Manifestation

作　　者：王卉菲 郭宇婧 刘艺 王敏[1] 贾赞慧[1] WANG Hui-fei;GUO Yu-jing;LIU Yi;WANG Min;JIA Zan-hui(The Second Hospital of Jilin University,Changchun 130000,China)

机构地区：[1]吉林大学第二医院

出　　处：《国际妇产科学杂志》2019年第6期670-673,共4页Journal of International Obstetrics and Gynecology

摘　　要：妊娠滋养细胞肿瘤(GTN)是由胎盘滋养细胞异常增生引起的一组异质性相关病变,可发生于足月产、早产、流产等任何类型的妊娠后,但其临床表现多种多样。现报道1例以脑出血为首发表现的滋养细胞肿瘤,患者入院时脑出血以致脑疝,完善相关检查后确诊为GTN合并脑转移及肺转移。提示对于育龄期特别是近期有妊娠史的患者,出现原因不明脑出血时应考虑到GTN脑转移的可能,对临床有一定的实际应用价值。Gestational trophoblastic neoplasia(GTN) is a group of heterogeneity related lesions caused by abnormal proliferation of placental trophoblastic cells, which can occur after full-term birth, preterm birth, miscarriage and other types of pregnancy, but its clinical manifestations are diverse. A case of trophoblastic tumor with cerebral hemorrhage as the primary manifestation is reported. The patient was admitted to hospital with cerebral hemorrhage and cerebral hernia, and was diagnosed as GTN with brain metastasis and pulmonary metastasis after completing relevant examinations. It is suggested that the possibility of brain metastasis of GTN should be considered when unexplained cerebral hemorrhage occurs in patients of reproductive age, especially those with recent pregnancy history, which has certain practical application value in clinical practice.

关 键 词：妊娠滋养细胞疾病 脑出血 肿瘤转移 药物疗法 联合 

分 类 号：R73[医药卫生—肿瘤]