支架取栓与动静脉联合溶栓对急性脑梗死患者神经功能及预后的影响研究  

Effect of stent thrombus removal and combined arteriovenous thrombolysis on neurological function and prognosis in patients with acute cerebral infarction

作　　者：郑文富[1] 蒋瑞姝[1] 易坤昌 ZHENG Wenfu;JIANG Ruishu;YI Kunchang(The Second Hospital of Longyan,Longyan 364000,China)

机构地区：[1]龙岩市第二医院

出　　处：《中国实用神经疾病杂志》2019年第18期2037-2042,共6页Chinese Journal of Practical Nervous Diseases

摘　　要：目的比较观察支架取栓与动静脉联合溶栓对急性脑梗死患者神经功能及预后的影响。方法选取2015-08-2018-08福建龙岩市第二医院收治的52例急性脑梗死患者为研究对象,按照随机数表法分为研究组(26例)与对照组(26例),研究组采用支架取栓予以治疗,对照组采用动静脉联合溶栓治疗,比较2组术前及术后第1、7天时的简明精神状态量表(mini-mental state examination,MMSE)评分,术前及术后3、6个月的改良Rankin量表(modified rankin scale,mRS)评分。结果术后第1、7天,研究组MMSE评分均明显高于对照组,2组比较差异有统计学意义(P<0.05);术后3、6个月,研究组mRS评分均明显低于对照组,2组比较差异有统计学意义(P<0.05)。结论支架取栓可有效恢复急性脑梗死患者的神经功能,提高患者预后,效果明显优于动静脉联合溶栓治疗,具有较高的临床应用价值。Objective The effects of stent thrombectomy and arteriovenous thrombolysis on neurological function and prognosis in patients with acute cerebral infarction were compared.Method A total of 52 patients with acute cerebral infarction admitted to the Second Hospital of Longyan City Fujian Province from 2015-08-2018-08 were selected as the study subjects.They were randomly divided into study group(26 cases)and control group(26 cases)according to random number table.The stent was treated with stent thrombectomy,and the control group was treated with arteriovenous thrombolysis.The scores of the mini-mental state examination(MMSE)before and after the first and seventh days were compared.And modified rankin scale(mRS)scores at 3 and 6 months postoperatively.Results On the 1 st and 7 th day after operation,the MMSE scores of the study group were significantly higher than those of the control group.The difference between the two groups was statistically significant(P<0.05).The mRS scores of the study group were 3 and 6 months after operation.Significantly lower than the control group,the difference between the two groups was statistically significant(P<0.05).Conclusion Stent thrombectomy can effectively restore the neurological function of patients with acute cerebral infarction and improve the prognosis of patients.The effect is better than that of arteriovenous thrombolysis.It has high clinical value.

关 键 词：支架取栓 动静脉联合溶栓 急性脑梗死 神经功能 血管再通率 

分 类 号：R743.33[医药卫生—神经病学与精神病学]