2004—2016年广州市膀胱癌发病情况及其趋势分析  

Analysis on Incidence of Bladder Cancer in Guangzhou City and Its Trend from 2004 to 2016

作　　者：许欢[1] 李科[1] 梁颖茹[1] 董航[1] 陈远源 XU Huan;LI Ke;LIANG Ying-ru;DONG Hang;CHEN Yuan-yuan(Guangzhou Center for Disease Control and Prevention,Guangzhou 510440,China)

机构地区：[1]广州市疾病预防控制中心

出　　处：《中国肿瘤》2019年第12期913-917,共5页China Cancer

摘　　要：[目的]分析广州市2004—2016年膀胱癌发病情况及其趋势。[方法]根据广州市肿瘤登记处收集的2004—2016年广州市膀胱癌病例数据,分析粗发病率、年龄别发病率、2000年中国人口标化发病率(中标率)、Segi’s世界人口标化发病率(世标率)、35~64岁截缩率、0~64岁累积发病率、0~74岁累积发病率、年均变化百分比(APC)。[结果]广州市2016年户籍居民膀胱癌新发病例502例,男、女世标发病率之比为3.88∶1(男性5.43/10万,女性1.40/10万),男、女世标发病率均呈平稳下降趋势(男性APC=-2.68%,95%CI:-3.7%^-1.6%,P<0.05;女性APC=-3.30%,95%CI:-4.80%^-1.70%,P<0.05)。城区、郊区和郊县世标发病率之比为1.51∶1.50∶1(城区3.44/10万,郊区3.42/10万,郊县2.28/10万),城区世标发病率呈明显下降趋势(APC=-5.25%,95%CI:-6.4%^-4.1%,P<0.05),郊区下降趋势无统计学意义(APC=-0.76%,95%CI:-2.6%~1.1%,P>0.05),郊县呈明显增长趋势(APC=6.15%,95%CI:2.2%~10.2%,P<0.05)。男、女性膀胱癌发病均从50岁开始快速上升,男性在85岁以上年龄组达到发病高峰(97.50/10万),女性在80~85岁年龄组达到发病高峰(30.30/10万)。[结论]广州市膀胱癌男性发病率明显高于女性,城郊发病差距逐渐缩小,应加强对50岁以上男性高危人群,尤其是郊县地区男性膀胱癌的有效防治。[Purpose]To analyze the incidence and its trend of bladder cancer in Guangzhou from2004 to 2016.[Methods]The data from Guangzhou Cancer Registry during 2004—2016 were collected to calculate the incidence of bladder cancer,age-specific incidence rate,age-standardized rate by China population 2000(ASR-C)and by Segi’s world standard population(ASR-W),truncated age-standardized rate by Segi’s world standard population,cumulative rate and annual percent change(APC).[Results]There were a total of 502 cases diagnosed as bladder cancer in 2016.The gender ratio of ASR-W was 3.88∶1(5.43/105 in male,1.40/105 in female).The ASR-W of bladder cancer had a stable downward trend in male(APC=-2.68%,95%CI:-3.7%^-1.6%,P<0.05)and female(APC=-3.30%,95%CI:-4.80%^-1.70%,P<0.05).The area ratio of ASR-W was 1.51∶1.50∶1(3.44/105 in urban,3.42/105 in suburb,2.28/105 in county).The ASR-W of bladder cancer in urban(APC=-5.25%,95%CI:-6.4%^-4.1%,P<0.05)had an obvious downward trend.There was no change observed in suburb(APC=-0.76%,95%CI:-2.6%~1.1%,P>0.05).The ASR-W of bladder cancer in county(APC=6.15%,95%CI:2.2%~10.2%,P<0.05)had an obvious upward trend.The incidence in male and female increased rapidly after 50 years old,and peaked at the age group of over 85 years old(97.50/105)in male and 80~84 years old(30.30/105)in female.[Conclusion]The incidence of bladder cancer is higher in male than that in female in Guangzhou City.The ASR-W gap was increasingly small between urban and country areas.We should focus on strengthening the prevention and control on bladder cancer in high risk group of male(>50 years old),especially in county areas.

关 键 词：膀胱癌 发病率 趋势 广东 

分 类 号：R737.14[医药卫生—肿瘤]