胃肠道肿瘤患者首次化疗期间肠内外营养支持的效果分析  

作　　者：林红 马文丽[1] 金海平 

机构地区：[1]浙江省台州医院,317100

出　　处：《浙江临床医学》2019年第11期1494-1495,共2页Zhejiang Clinical Medical Journal

基　　金：浙江省医药卫生科技计划项目(2016KYB147)。

摘　　要：目的 探讨胃肠道肿瘤患者首次化疗期间肠内外营养支持治疗的效果.方法 将胃肠道肿瘤患者130例随机分为对照组与观察组,各65例.对照组化疗期间给予单纯肠外营养支持疗法,观察组给予肠内外综合支持疗法;比较两组首次化疗后机体免疫力、营养状态、并发症发生率等指标.结果 化疗3周后,观察组的IgG、IgM及CD4+/CD8+水平均高于对照组(P<0.05);观察组血清白蛋白、血红蛋白及前白蛋白水平均高于对照组(P<0.05);观察组化疗期间并发症发生率13.85%,低于对照组32.31%(P<0.05).结论 胃肠道肿瘤患者首次化疗期间给予肠内外综合支持疗法后,可明显提高患者的机体免疫力和营养状态,降低并发症发生率,有助于改善患者的预后.Objective To explore the effect of gastroenteric tumor patients during the first chemotherapy with enteral and parenteral nutrition support.Methods 130 cases of gastroenteric tumor patients were randomly divided into control group and observation group,65 cases in each group.The control group was carried out simple parenteral nutrition support therapy during the first chemotherapy,and the observation group was given enteral and parenteral nutrition support.The indexes of body immunity,nutritional status and incidence rate of complications were compared between the two groups after the first chemotherapy.Results After 3 weeks of chemotherapy,the levels of IgG,IgM and CD4+/CD8+in the observation group were all higher than the control group(P<0.05).The levels of serum albumin,hemoglobin and prealbumin in the observation group were all higher than the control group(P<0.05).But the incidence rate of the observation group during the first chemotherapy was 13.85%,lower than the control group(32.31%,P<0.05).Conclusion Gastroenteric tumor patients after enteral and parenteral nutrition support during the first chemotherapy,it can obviously raise body immunity and nutritional status of patients,cut down the incidence rate of complications.It is good for improving patients’prognosis.

关 键 词：胃肠道肿瘤 化疗 肠内营养 肠外营养 效果评价 

分 类 号：R73[医药卫生—肿瘤]