清肝息风汤辅助治疗多发性抽动症临床研究  

The Clinical Research on Qinggan Xifeng Decoction in the Treatment of Multiple Tics

作　　者：巩克波[1] 刘远昌[2] 武志华[3] GONG Kebo;LIU Yuanchang;WU Zhihua(Department of Traditional Chinese Medicine,Jinan Children's Hospital,Shandong Province,Jinan 250022,China;Department of Endocrinology,Jinan Children's Hospital,Shandong Province,Jinan 250022,China;Rehabilitation Department,Jinan Children's Hospital,Shandong Province,Jinan 250022,China)

机构地区：[1]济南市儿童医院中医科,山东济南250022 [2]济南市儿童医院神经内分泌科,山东济南250022 [3]济南市儿童医院康复科,山东济南25002

出　　处：《中国中医药现代远程教育》2019年第23期46-49,共4页Chinese Medicine Modern Distance Education of China

摘　　要：目的研究自拟清肝息风汤辅助治疗多发性抽动症的疗效。方法将100例符合标准的多发性抽动症患者随机分为治疗组和对照组各50例(实际完成研究治疗组47例,对照组46例),2组均给予盐酸硫必利片口服,治疗组在西药治疗的基础上合用自拟清肝息风汤口服,疗程为3个月,观察治疗前后中医证候疗效、临床疗效耶鲁抽动症整体严重度量表(YGTSS)评分,并观察不良反应量表(TESS)总分。结果治疗后,治疗组中医证候疗效、YGTSS评分改善明显优于对照组(P<0.05),TESS总分明显低于对照组(P<0.05)。结论自拟清肝息风汤治疗多发性抽动症,具有较好的疗效,安全性高。Objective To study the auxiliary curative effect of self-prepared Qinggan Xifeng decoction in treating multiple tics.Methods The 100 patients with the standard of multiple tics were divided into treatment group and control group,with 50 cases in each group(47 cases in the treatmen group and 46 in control group actuallycompleted the research).The two groups were given tiapride hydrochloride tablets,while the treatment group was given self-prepared Qinggan Xifeng decoction.The treatment course was 3 months.The TCM curative effect,clinical efficacy of Yale twitch disease severity scale(YGTSS)and adverse side effects scale were observed.Results After treatment,the effect in TCM curative effect and YGTSS score of the treatment group was better than that of the control group(P<0.05).And the TESS score of the treatment group were significantly lower than that of the control group(P<0.05).Conclusion The self-prepared Qinggan Xifeng decoction has better curative effect and security.

关 键 词：清肝息风汤 多发性抽动症 肝亢风动证 惊风 

分 类 号：R74[医药卫生—神经病学与精神病学]