急性脑梗死患者血浆D二聚体、纤维蛋白原、神经元特异性烯醇化酶联合检测的临床价值  

Clinical Value of Plasma of D-dimer、Fibrinogen and Neuron Specific Enolase combined Detection in Patients with Acute Cerebral Infarction

作　　者：陈峻[1] 徐升强[1] 曹文操[1] CHEN Jun;XU Sheng-qiang;CAO Wen-cao(Department of laboratory,Wuhan No.1 hospital,Wuhan,430022,China)

机构地区：[1]武汉市第一医院检验科

出　　处：《血栓与止血学》2019年第6期913-914,916,共3页Chinese Journal of Thrombosis and Hemostasis

摘　　要：目的为探讨急性脑梗死(ACI)患者血浆D二聚体(D-D)、纤维蛋白原(Fbg)、神经元特异性烯醇化酶(NSE)联合检测的临床价值。方法采用SysmexCS2000 i全自动血凝仪对150例ACI患者及100例健康体检者血浆D-D、Fbg、NSE分别进行检测,并进行比较。结果 ACI患者血浆D-D、Fbg、NSE水平明显高于健康对照组,差异有统计学意义(P<0.01)。结论联合检测血浆D-D、Fbg、NSE对于ACI患者的早期诊断及病程变化监测具有重要临床价值。Objective To investigate the acute cerebral infarction(ACI)patients with plasma D-dimer(D-D),fibrinogen(Fbg),and neuron specific enolase(NSE)combined detection of clinical value.Methods SysmexCS2000 i automatic blood coagulation analyzer 150 cases with ACI patients and 100 cases of healthy persons plasma D-D,Fbg and NSE were respectively detected and compared.,Results The ACI patients with plasma D-D,Fbg and NSE levels were significantly higher than healthy controls(P<0.01);Conclusion Combined detection of plasma D-D,Fbg and NSE has important clinical value for early diagnosis and course change monitoring in patients withACI.

关 键 词：急性脑梗死 D二聚体 纤维蛋白原 神经元特异性烯醇化酶 

分 类 号：R743[医药卫生—神经病学与精神病学]