生长抑素联合内镜下注射硬化剂治疗肝硬化并食管胃底静脉曲张破裂出血的疗效评价  

Evaluation of the efficacy of somatostatin combined with endoscopic injection of sclerosing agent in the treatment of liver cirrhosis with esophagogastric variceal bleeding

作　　者：钟海彬[1] ZHONG Hai-bin(Wuhua County Hospital of Traditional Chinese Medicine,Meizhou 514400,China)

机构地区：[1]五华县中医医院

出　　处：《中国实用医药》2019年第36期95-97,共3页China Practical Medicine

摘　　要：目的分析生长抑素联合内镜下注射硬化剂治疗肝硬化并食管胃底静脉曲张破裂出血患者的临床疗效。方法90例肝硬化并食管胃底静脉曲张破裂出血患者,依照治疗方法不同分为对照组(12例)与观察组(78例)。对照组使用生长抑素治疗,观察组在对照组的基础上联合内镜下注射硬化剂治疗。观察比较两组治疗效果和术后第1、3、6个月出血复发情况。结果对照组患者治疗有效率58%低于观察组的87%,差异有统计学意义(P<0.05)。观察组患者治疗的第1、3、6个月出血复发率分别为21%、13%、15%均低于对照组的50%、67%、50%,差异有统计学意义(P<0.05)。结论对肝硬化并食管胃底静脉曲张破裂出血患者使用生长抑素联合内镜下注射硬化剂治疗,能取得满意效果,值得推广。Objective To analyze the clinical efficacy of somatostatin and somatostatin combined with endoscopy in the treatment of liver cirrhosis with esophagogastric variceal bleeding.Methods A total of 90 cases of liver cirrhosis with esophagogastric variceal bleeding were divided into control group(12 cases)and observation group(78 cases).The control group was treated by somatostatin,and the observation group was treated by endoscopic injection of sclerosing agent on the basis of the control group.The therapeutic effect and recurrence of bleeding at 1 st,3 rd and 6 th months of treatment was observed and compared between the two groups.Results The effective rate of treatment was 58%in the control group,which was lower than 87%in the observation group,and the difference was statistically significant(P<0.05).The recurrence of bleeding at 1 st,3 rd and 6 th months of treatment was 21%,13%and 15%respectively,which was lower than 50%,67%and 50%in the control group,and their difference was statistically significant(P<0.05).Conclusion Somatostatin combined with endoscopy shows satisfactory effect in the treatment of liver cirrhosis with esophagogastric variceal bleeding,and it is worthy of further promotion.

关 键 词：生长抑素 内镜下注射硬化剂 肝硬化 食管胃底静脉曲张破裂出血 

分 类 号：R57[医药卫生—消化系统]