腹腔间隔室综合征压力-容积曲线的实验研究  

Experimental Study on the Pressure-volume Curve of Abdominal Compartment Syndrome

作　　者：陈勇 王宏业 CHEN Yong;WANG Hong-ye(Gastroenterology,The Affiliated Hospital of Shanxi Datong University,Datong Shanxi,037004)

机构地区：[1]山西大同大学附属医院消化内科

出　　处：《山西大同大学学报（自然科学版）》2019年第6期47-48,94,共3页Journal of Shanxi Datong University(Natural Science Edition)

基　　金：山西省重点研发计划（指南）项目[201603D321054]

摘　　要：目的制作腹腔高压液体动物模型,探索腹腔间隔室综合症压力-容积曲线变化规律。方法以实验兔为研究对象,以生理盐水注入腹腔制作腹腔压增高模型。腹膜腔内注入生理盐水,每注入100 m L测压1次并记录。绘制腹腔压随生理盐水量增加而升高的曲线图,分析腹腔压升高时生理盐水量与腹腔压的关系。结果在注入1000 mL生理盐水后腹腔压力开始升高,回归方程为:Y=-9.27+29.83 X。结论随着腹腔内容物的逐渐增加,腹腔压力在突破临界点后呈现快速递增的趋势,即使腹腔内容物少量增加,也可引起腹腔压力的急剧升高。Objective To explore the change of pressure volume curve of abdominal compartment syndrome by making animal model of abdominal high pressure liquid.Methods Intra-abdominal hypertension rabbit model is made by NS.Measure and record the pressure when per 100 mL NS is infused into the abdomen.draw pressure-volume curve.Regression analysis is used to study the functional relation between them.Results Intro-abdominal pressure begin to increase when 1000 mL NS is infused into the abdomen.The regression equation is:Y=-9.27+29.83 X.Conclusion With the gradual increase of abdominal contents,the abdominal pressure appears to increase rapidly after breaking the critical point.Even if the abdominal content increases in small quantities,it can cause a sharp increase in abdominal pressure.

关 键 词：腹腔间隔室综合征 压力-容积曲线 新西兰兔 

分 类 号：R572[医药卫生—消化系统]