肝内胆管癌的临床诊断策略  

Research advances in the clinical diagnosis of intrahepatic cholangiocarcinoma

作　　者：陈志升 唐陈伟 汤朝晖[2] 童焕军 金志伟 CHEN Zhisheng;TANG Chenwei;TANG Zhaohui(Department of General Surgery, Shanghai Eighth People’s Hospital, Shanghai 200235, China)

机构地区：[1]上海市第八人民医院普外科,上海200235 [2]上海交通大学医学院附属新华医院普外科,上海200092

出　　处：《临床肝胆病杂志》2019年第12期2638-2643,共6页Journal of Clinical Hepatology

摘　　要：肝内胆管癌(ICC)是源于二级及以上分支胆管上皮细胞的肝恶性肿瘤,具有早期症状隐匿,恶性程度较高,病情进展迅速,容易发生淋巴结转移、肝内转移及血管侵犯等特点,患者预后状况极差。早期诊断可提高ICC的根治切除率,改善患者预后。目前,ICC术前诊断主要依靠影像学、实验室检查及病理学检查。此外,近年一些新兴的诊断方法也开始用于ICC的诊断。但组织病理学检查仍是目前明确诊断ICC的唯一方法。本文旨在对ICC的诊断研究最新进展进行综述。Intrahepatic cholangiocarcinoma(ICC)is a malignant liver tumor derived from the epithelial cells of the second-or higher-order branch of the bile duct,with the features of insidious early symptoms,high degree of malignancy,rapid disease progression,lymph node metastasis,intrahepatic metastasis,and vascular invasion,and such patients tend to have poor prognosis.Early diagnosis can improve the radical resection rate and prognosis of ICC.At present,the preoperative diagnosis of ICC mainly relies on imaging technology,laboratory examination,and pathological examination.In addition,some new diagnostic methods have also been used in the diagnosis of ICC in recent years,but histopathological examination remains the only method for the diagnosis of ICC.This article reviews the latest research advances in the diagnosis of ICC.

关 键 词：胆管肿瘤 诊断 临床实验室技术 诊断显像 病理学 临床 分子生物学 

分 类 号：R735.8[医药卫生—肿瘤]