腹腔镜辅助与传统开放远端胃癌D2根治术对胃癌患者的近期效果对比观察  

Comparative observation of short-term effects of laparoscopic assisted and conventional open distal gastric cancer D2 radical surgery on patients with gastric cancer

作　　者：陈德虎 刘贵远[1] 尤小兰[1] 曹赣[1] Chen Dehu;Liu Guiyuan;You Xiaolan;Cao Gan(Taizhou People's Hospital,Taizhou,Jiangsu,225300,China)

机构地区：[1]泰州市人民医院

出　　处：《当代医学》2019年第34期58-60,共3页Contemporary Medicine

基　　金：泰州市科技支撑计划（社会发展）项目（TS201732)

摘　　要：目的探讨腹腔镜辅助与传统开放远端胃癌D2根治术对胃癌患者的近期效果。方法选择2013年1月至2019年7月本院收治的40例胃癌患者为研究对象,应用随机抽签法分为对照组(20例)与研究组(20例)。对照组实施常规开放远端胃癌D2根治术,研究组实施腹腔镜辅助远端胃癌D2根治术。结果研究组的手术总时间为(255.50±28.35)min,长于对照组,差异有统计学意义(P<0.05);研究组的切口平均长度为(5.50±0.20)cm,术后排气时间长为(4.05±0.65)d,术后下床走动时长为(2.80±0.75)d,术后总住院天数为(12.50±2.65)d,均短于对照组,差异有统计学意义(P<0.05);研究组的术中平均出血量为(183.45±28.95)ml,均少于对照组,差异有统计学意义(P<0.05);两组治疗前的hs-CRP、TNF-α、IL-6比较,差异无统计学意义;研究组治疗后的hs-CRP为(20.65±4.20)mg/L,TNF-α为(23.40±4.30)μg/L,IL-6为(43.50±5.50)ng/L,均低于对照组,差异有统计学意义(P<0.05);研究组的手术后并发症发生率为5.00%,低于对照组,差异有统计学意义(P<0.05)。结论对远端胃癌患者实施腹腔镜辅助远端胃癌D2根治术的近期效果更优于常规开放远端胃癌D2根治术,值得临床推广使用。Objective To investigate the short-term effect of laparoscopic assisted and traditional open distal gastric cancer D2 radical surgery on gastric cancer patients. Methods Forty patients with gastric cancer admitted to our hospital from January 2013 to July 2019 were enrolled in the study. They were randomly divided into control group(20 cases) and study group(20 cases). The control group underwent routine open distal gastric cancer D2 radical surgery, and the study group underwent laparoscopic assisted distal gastric cancer D2 radical surgery. Results The total operation time of the study group was(255.50±28.35) min, which was longer than that of the control group, and the difference was statistically significant(P<0.05). The average length of the incision in the study group was(5.50±0.20) cm,(4.05±0.65) d, the length of postoperative ambulation was(2.80±0.75) d, and the total length of hospital stay was(12.50±2.65) d, which was shorter than the control group, and the difference was statistically significant(P<0.05). The mean intraoperative blood loss of the study group was(183.45±28.95) ml, which was less than the control group, and the difference was statistically significant(P<0.05). Before treatment the two group of hs-CRP, TNF-α, IL-6 were compared. The difference was not statistically significant. The hs-CRP of the study group was(20.65±4.20) mg/L, TNF-α was(23.40±4.30) μg/L, and IL-6 was(43.50±5.50) ng/L, were lower than the control group, the difference was statistically significant(P<0.05). the postoperative complication rate of the study group was 5.00%,which was lower than the control group, and the difference was statistically significant(P<0.05). Conclusion The short-term effect of laparoscopic assisted distal gastric cancer D2 radical resection for patients with distal gastric cancer is better than conventional open distal gastric cancer D2 radical surgery, which is worthy of clinical application.

关 键 词：远端胃癌 传统开放远端胃癌D2根治术 腹腔镜 近期效果 

分 类 号：R73[医药卫生—肿瘤]