Application of multiple Roux-en-Y hepaticojejunostomy reconstruction by formation of bile hilar duct lake in the operation of hilar cholangiocarcinoma  

作　　者：Xiao-Jun Yang Xiao-Hua Dong Shi-Yong Chen Biao Wu Yu He Bao-Long Dong Bing-Qiang Ma Peng Gao 

机构地区：[1]Department of General Surgery,Gansu Provincial Hospital,Lanzhou 730000,Gansu Province,China [2]School of Clinical Medicine,Ningxia Medical University,Yinchuan 750000,Ningxia Hui Autonomous Region,China [3]School of Clinical Medicine,Gansu University of Chinese Medicine,Lanzhou 730000,Gansu Province,China

出　　处：《World Journal of Clinical Cases》2020年第1期68-75,共8页世界临床病例杂志

基　　金：Supported by National Natural Science Foundation of China,No.81260326 and No.81660398;Natural Science Foundation of Gansu Province,No.17JR5RA034

摘　　要：BACKGROUND Hilar cholangiocarcinoma is the most common malignant tumor of the extrahepatic bile duct.Until now,radical resection has been the most effective method for the long-term survival of patients with the disease.However,many problems have emerged in the field of hepatobiliary surgery for a long time,including complex surgical procedures,low resection rate,and postoperative complications.We have adopted the“multiple Roux-en-Y hepaticojejunostomy reconstruction by formation of a bile duct lake”technique in the treatment of hilar cholangiocarcinoma since 2008,and obtained satisfactory short-and longterm results.AIM To examine the feasibility of the application of multiple Roux-en-Y hepaticojejunostomy reconstruction by formation of a bile duct lake in the operation of hilar cholangiocarcinoma METHODS A retrospective analysis was performed for the clinical data,surgical methods,and results of 76 patients with hilar cholangiocarcinoma who were treated with hilar bile duct lake-forming multiple Roux-en-Y hepaticojejunostomy reconstruction at Gansu Provincial Hospital.RESULTS In all 76 cases,the operation was successful and no operative death occurred.The mean(range)operation time was 215.4±53.5 min(124–678 min),and the amount of bleeding during the operation was 428.2±63.8 mL(240–2200 mL).The overall 1-year survival rate was 78.9%,and the 3-year survival rate was 32.8%.CONCLUSION The multiple Roux-en-Y hepaticojejunostomy reconstruction technique with formation of a bile duct lake is safe and effective for the surgical treatment of hilar cholangiocarcinoma.BACKGROUND Hilar cholangiocarcinoma is the most common malignant tumor of the extrahepatic bile duct. Until now, radical resection has been the most effective method for the long-term survival of patients with the disease. However, many problems have emerged in the field of hepatobiliary surgery for a long time,including complex surgical procedures, low resection rate, and postoperative complications. We have adopted the "multiple Roux-en-Y hepaticojejunostomy reconstruction by formation of a bile duct lake" technique in the treatment of hilar cholangiocarcinoma since 2008, and obtained satisfactory short-and longterm results.AIM To examine the feasibility of the application of multiple Roux-en-Y hepaticojejunostomy reconstruction by formation of a bile duct lake in the operation of hilar cholangiocarcinoma.METHODS A retrospective analysis was performed for the clinical data, surgical methods,and results of 76 patients with hilar cholangiocarcinoma who were treated with hilar bile duct lake-forming multiple Roux-en-Y hepaticojejunostomy reconstruction at Gansu Provincial Hospital.RESULTS In all 76 cases, the operation was successful and no operative death occurred. The mean(range) operation time was 215.4 ± 53.5 min(124–678 min), and the amountof bleeding during the operation was 428.2 ± 63.8 m L(240–2200 m L). The overall1-year survival rate was 78.9%, and the 3-year survival rate was 32.8%.CONCLUSION The multiple Roux-en-Y hepaticojejunostomy reconstruction technique with formation of a bile duct lake is safe and effective for the surgical treatment of hilar cholangiocarcinoma.

关 键 词：Hilar cholangiocarcinoma Bile duct lake HEPATICOJEJUNOSTOMY 

分 类 号：R73[医药卫生—肿瘤]