自身免疫性脑炎的早期诊断  

Early diagnosis of autoimmune encephalitis

作　　者：季涛云[1] 姜玉武[1] Ji Taoyun;Jiang Yuwu(Department of Pediatrics,Peking University First Hospital,Beijing 100034,China)

机构地区：[1]北京大学第一医院儿科,100034

出　　处：《中华实用儿科临床杂志》2019年第24期1851-1854,共4页Chinese Journal of Applied Clinical Pediatrics

摘　　要：自身免疫性脑炎是一类可治疗的中枢神经系统自身免疫性疾病,抗N-甲基-D-天门冬氨酸受体(NMDAR)脑炎是其中最常见的种类。部分自身免疫性脑炎可通过特异的自身抗体辅助诊断,但过度依靠自身抗体检测可导致治疗的延误。现对儿童抗NMDAR脑炎、抗体阴性的自身免疫性脑炎特点进行综述,以提高广大儿科医师对此病的认识。Autoimmune encephalitis is a group of treatable autoimmune diseases of central nervous system.Anti-N-methyl-D-aspartate receptor(NMDAR)encephalitis is one of the most common autoimmune encephalitis.Some of autoimmune encephalitis can be confirmed by specific autoantibodies,but excessive dependence on autoantibody detection usually leads to delayed treatment.This article reviews the clinical presentations of pediatric anti-NMDAR encephalitis and the antibody-negative autoimmune encephalitis so as to improve the pediatricians understanding on the diseases.

关 键 词：自身免疫性脑炎 抗N-甲基-D-天门冬氨酸受体脑炎 抗体阴性的自身免疫性脑炎 

分 类 号：R742[医药卫生—神经病学与精神病学]