基于计算机辅助设计与3D打印技术的血管化腓骨游离移植修复下颌骨缺损的应用研究  

Application research of vascularized fibular free grafting to repair mandibular defects based on computeraided design and 3D printing technology

作　　者：穆婷 马成 冯浩然 王爽 何雨亮 黄旋平[1,2,3,4] MU Ting;MA Cheng;FENG Haoran;WANG Shuang;HE Yu-liang;HUANG Xuanping(College of Stomatology,Guangxi Medical University,Nanning 530021,China;不详)

机构地区：[1]广西医科大学附属口腔医院,南宁530021 [2]广西口腔颌面修复与重建研究重点实验室,南宁530021 [3]广西颅颌面畸形临床医学研究中心,南宁530021 [4]颌面外科疾病诊治研究重点实验室,南宁530021 [5]安徽医科大学第四附属医院,合肥230002

出　　处：《实用医学杂志》2019年第23期3638-3643,共6页The Journal of Practical Medicine

基　　金：广西医疗卫生适宜技术开发与推广应用项目（编号：S201687）;广西科学研究与技术开发计划项目（编号：桂科攻1598012-18）

摘　　要：目的探讨基于计算机辅助设计(computer-aided design,CAD)与3D打印技术的血管化腓骨游离移植修复下颌骨缺损的应用效果。方法选择22例需行下颌骨病变切除及重建的患者,并随机分为A、B两组,A组采用CAD与3D打印技术的血管化腓骨游离移植修复下颌骨缺损,B组采用传统血管化腓骨游离移植修复下颌骨缺损,记录手术时间,将术前术后三维图像重叠,分别测量下颌骨各标志点的移动距离,并将两组结果进行统计分析。结果A组和B组平均手术时间分别为(8.28±1.17)h和(9.45±0.94)h,差异有统计学意义(P=0.018)。A组下颌颏顶点的移动距离较B组下颌颏顶点的移动距离短,A组各位置点的总体移动距离较B组各位置点的总体移动距离短,且差异均有统计学意义,其余位置点平均移动距离未见明显差异。结论CAD与3D打印技术在血管化腓骨游离移植修复下颌骨缺损方面,可以减少手术时间,较为理想的恢复颌面外形,获得较高的精确度。Objective To investigate the application effect of vascularized fibular free grafting to repair mandibular defects based on computer-aided design(CAD)and 3 D printing technology.Methods A total of 22 patients requiring resection and reconstruction of mandibular lesions were randomly divided into two groups.Patients of group A were treated with CAD and 3 D printing techniques for vascularized fibular free grafting to repair mandibular defects.And patients of Group B were treated with conventional vascularized fibular free transplantation.The operation time was recorded.The three-dimensional images of preoperative and postoperative were superimposed.The moving distances of the mandibular landmarks were measured,and the results of the two groups were statistically analyzed.Results The mean operative time in group A and group B was(8.28±1.17)h and(9.45±0.94)h,respectively(P=0.018),the difference between the two groups was statistically significant.The moving distance of mandibular chin apex in group A was shorter than that in group B.In addition,the overall moving distance of each point in group A was shorter than that in group B,and the difference was statistically significant.There was no significant difference in the average moving distance of other points.Conclusion CAD and 3 D printing technology can reduce the operation time in the treatment of mandibular defects with vascularized fibular free grafting,and it is ideal to restore the maxillofacial shape and obtain higher precision.

关 键 词：计算机辅助设计与3D打印技术 血管化腓骨游离移植瓣 下颌骨缺损 精确度 

分 类 号：R78[医药卫生—口腔医学]