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作 者:崔仪 韩振国[2] CUI Yi;HAN Zhenguo(Graduate School of Shanxi Medical University,Shanxi Province,Taiyuan030001,China;Department of General Surgery,Shanxi Da Hospital,Shanxi Academy of Medical Sciences,Shanxi Province,Taiyuan030010,China)
机构地区:[1]山西医科大学研究生学院,山西太原030001 [2]山西医学科学院山西大医院普外科,山西太原030010
出 处:《中国医药导报》2020年第1期42-45,共4页China Medical Herald
基 金:山西省重点研发计划(指南)项目(201603D321052)
摘 要:胃肠道间质瘤(GISTs)是一种消化道最常见的间叶源性肿瘤。外科手术是局限型或潜在可切除GISTs患者的首选治疗方式,但是,患者在接受手术治疗后,仍有较高的复发率。靶向药物的出现及手术方式的进步使目前GISTs的治疗呈现出微创化、阶段化、多学科化的特点,能够较好改善GISTs患者的生活水平。鉴于GISTs致病机制复杂性、临床治疗和预后的病情不稳定性,现对GISTs患者的治疗方式进行阐述。Gastrointestinal stromal tumors(GISTs) are the most common mesenchymal tumors of the digestive tract.Surgery is the first choice of treatment for patients with localized or potentially resectable GISTs, but patients still have a high recurrence rate after receiving surgical treatment. The emergence of targeted drugs and the progress of surgical methods have made the current treatment of GISTs appear to be minimally invasive, phased, and multidisciplinary,which can better improve the living standards of patients with gastrointestinal stromal tumors. In view of the complexity of the pathogenesis of GISTs and the instability of clinical treatment and prognosis, the treatment of patients with GISTs is now described.
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