经皮颈动脉支架植入术治疗颈动脉狭窄的远期疗效观察  

Long-term efficacy of percutaneous carotid artery stenting on carotid stenosis

作　　者：李渊[1] Li Yuan(Department of Neurological Surgery,Linfen People's Hospital,Linfen 044000,China)

机构地区：[1]山西省临汾市人民医院神经外科,041000

出　　处：《中国实用医刊》2019年第21期45-48,共4页Chinese Journal of Practical Medicine

摘　　要：目的探讨颈动脉狭窄患者采用经皮颈动脉支架植入术治疗的远期疗效.方法选取2015年7月至2018年6月在临汾市人民医院就诊的颈动脉狭窄患者68例,根据随机数字表法分为两组,每组34例.对照组采用药物治疗,观察组采用经皮颈动脉支架植入术治疗.比较两组凝血因子水平、那维亚神经卒中量表(SSS)评分、巴塞尔(Barthel)指数及远期预后效果.结果治疗后,观察组纤维蛋白原(FIB)、活化部分凝血活酶时间(APPT)水平均高于对照组,差异有统计学意义(P<0.05).观察组治疗后Barthel指数高于对照组,SSS评分低于对照组,差异有统计学意义(P<0.05).观察组冠状动脉缺血、死亡发生率与对照组比较差异未见统计学意义(P>0.05).观察组脑卒中发生率(2.94%,1/34)低于对照组(23.53%,8/34),差异有统计学意义(P<0.05).结论经皮颈动脉支架植入术治疗可改善颈动脉狭窄患者神经功能及日常生活能力,降低脑卒中发生率,但其术后将在一定程度上影响患者凝血因子水平.Objective To investigate the long-term effects of percutaneous carotid stent implantation on patients with carotid artery stenosis.Methods Sixty-eight patients with carotid artery stenosis who were treated in Linfen People's Hospital from July 2015 to June 2018 were selected and grouped according to random number table method,with 34 cases in each group.The control group was treated with drugs,while the observation group was treated by percutaneous carotid artery stent implantation.The levels of coagulation factors,Scandinavian stroke scale(SSS),Barthel index and Iong-terni prognosis were compared between the two groups.Results After treatment,the levels of fibrinogen(FIB)and activated partial thromboplastin time(APPT)in the observation group were higher than those in the control group(P<0.05).After treatment,the Barihel index in the observation group was higher than that in the control group,and the SSS score was lower than that in the control group(P<0.05).There was no significant difference in the incidence of coronaiy ischemia or mortality rate between the observation groupand the control group(P>0.05).The incidence of stroke in the observation group(2.94%,1/34)was significantly lower than that in the contTol group(23.53%,8/34),P<0.05.Conclusions Percutaneous carotid artery stent implantation can improve the neurological function and daily living activities of patients with carotid artery stenosis and reduce the incidence of stroke.However,it can affect the level of coagulation factors to some extent.

关 键 词：颈动脉狭窄 经皮颈动脉支架植入术 药物治疗 远期疗效 

分 类 号：R743.3[医药卫生—神经病学与精神病学]