双相障碍稳定期患者前瞻记忆与情感气质的相关分析  

Relationship between prospective memory and temperament in patients with euthymic bipolar disorder

作　　者：吴庆[1] 王莹[1] 于海宁 费龙才[1] Wu Qing;Wang Ying;Yu Haining;Fei Longcai(Department of Clinical Psychology,the Fourth People's Hospital of Hefei,Hefei 230022,China)

机构地区：[1]合肥市第四人民医院临床心理科,230022

出　　处：《中华行为医学与脑科学杂志》2019年第12期1070-1074,共5页Chinese Journal of Behavioral Medicine and Brain Science

基　　金：国家自然科学基金项目(81973064);安徽医科大学科学研究资助项目(2019xkj207);合肥市第四人民医院科研支持项目(2019001)。

摘　　要：目的探讨双相障碍稳定期患者基于事件前瞻记忆(event-based prospective memory,EBPM)和基于时间前瞻记忆(time-based prospective memory,TBPM)的特征,以及前瞻记忆与其情感气质的关系。方法共纳入50例双相障碍患者(患者组)以及45例人口学资料相匹配的健康对照者(对照组),采用前瞻记忆测试评估前瞻记忆,情感气质量表简版(temperament evaluation of the memphis,TEMPS-A)评估患者的情感气质。采用t检验比较患者组与对照组前瞻记忆与情感气质差异,采用Pearson相关性分析情感气质与稳定期双相障碍前瞻记忆的相关性。结果与对照组[EBPM:(4.18±0.83)分、TBPM:(3.89±0.75)分]相比,患者组的EBPM评分[(3.66±0.69)分]和TBPM评分[(3.06±0.96)分]低,差异有统计学意义(t=-3.313,P<0.01;t=-4.674,P<0.01)。患者组TEMP-A总分和5个因子分均高于对照组[总分(18.82±4.49)分,(9.69±3.37)分,t=11.106,P<0.01]。相关分析显示,患者组TBPM评分与抑郁气质呈显著负相关(r=-0.425,P=0.002)。结论双相障碍稳定期患者EBPM和TBPM均存在损害,患者TBPM与抑郁气质存在相关性。Objective To investigate the event-based prospective memory(EBPM)and time-based prospective memory(TBPM)in patients with euthymic bipolar disorder and to explore the relationships between prospective memory and temperament.Methods Fifty patients with euthymic bipolar disorder(case group)and forty-five demographic characteristic matched healthy controls(control group)were recruited.The neuropsychological battery of tests including EBPM and TBPM tasks were used to measured the prospective memory,and all participants completed the Chinese version of short temperament evaluation of the memphis(TEMPS-A).The differences in prospective memory and temperament between the case group and control group were compared by t test.Pearson correlation analysis was used to analyze the correlation between prospective memory and temperament.Results A statistically significant in EBPM was observed between patients with euthymic bipolar disorder and health controls((3.66±0.69)vs(4.18±0.83),t=-3.313,P<0.01)and the same result was showed in TBPM((3.06±0.96)vs(3.89±0.75),t=-4.674,P<0.01).The total score of TEMPS-A((18.82±4.49)vs(9.69±3.37),t=11.106,P<0.01)and the scores of all the subscales were higher in case group than those in control group.The negative correlation was showed between the scores of depression temperament and TBPM(r=-0.425,P=0.002)in the case group.Conclusion The results suggest both EBPM and TBPM have impaired,and TBPM correlates with depression temperament moderately in the patients with euthymic bipolar disorder.

关 键 词：双相障碍 前瞻记忆 气质 

分 类 号：R749.4[医药卫生—神经病学与精神病学]