中性粒细胞百分比及红细胞体积分布宽度与进展性卒中的相关性研究  

Relationship between the percentage of neutrophils and the width of erythrocyte volume distribution and progressive stroke

作　　者：彭俊 胡乐乐 邓秀梅 毛诗贤 PENG Jun;HU Lele;DENG Xiumei(Guizhou Medical University,Guiyang 550000,China)

机构地区：[1]贵州医科大学,贵州贵阳550000 [2]贵州医科大学附属医院神经内科,贵州贵阳550000 [3]贵州医科大学附属医院综合病房,贵州贵阳550000 [4]贵州医科大学附属白云医院神经内科,贵州贵阳550001

出　　处：《中风与神经疾病杂志》2019年第12期1079-1082,共4页Journal of Apoplexy and Nervous Diseases

摘　　要：目的探讨中性粒细胞百分比及红细胞分布宽度与进展性卒中的关系。方法选自2018年1月-2018年12月间贵州医科大学附属医院神经内科收治的121例急性脑梗死患者,依据是否出现卒中进展分为进展性卒中组(39例)和非进展性卒中组(82例),比较两组患者基本资料、临床特征。分析中性粒细胞百分比及红细胞分布宽度与进展性卒中的关系。结果与非进展性卒中组比较,进展性卒中组中性粒细胞百分比[(73.63±9.99)vs(64.87±10.33)]、红细胞分布宽度[(14.17±1.33)g/L vs(13.10±1.03)g/L]增高,差异均有统计学意义(P<0.05)。多因素Logistic回归分析显示中性粒细胞百分比(OR=1.076,95%CI 1.023~1.131,P=0.005)、红细胞分布宽度(OR=2.068,95%CI 1.249~3.425,P=0.005)。结论中性粒细胞百分比及红细胞分布宽度是进展性卒中的独立预测因素。Objective To investigate the relationship between the percentage of neutrophils and the width of erythrocytes and progressive stroke.Methods A total of 121 patients with acute cerebral infarction admitted to the department of neurology of affiliated hospital of guizhou medical university from January 2018 to December 2018 were selected and divided into the progressive stroke group(39 cases)and the non-progressive stroke group(82 cases)according to whether or not stroke progression occurred.Basic data and clinical features of the patients in the two groups were compared.The relationship between the percentage of neutrophils and the width of erythrocytes was analyzed.Results Compared with the non-progressive stroke group,the percentage of neutrophils[(73.63±9.99)vs(64.87±10.33)]and the distribution width of red blood cells[(14.17±1.33)g/L vs(13.10±1.03)g/L]in the progressive stroke group were increased,with statistically significant differences(P<0.05).Multivariate Logistic regression analysis showed the percentage of neutrophils(OR=1.076,95%CI 1.023~1.131,P=0.005)、(OR=2.068,95%CI 1.249~3.425,P=0.005).Conclusion The percentage of neutrophils and the width of erythrocytes were independent predictors of progressive stroke.

关 键 词：中性粒细胞百分比 红细胞分布宽度 进展性卒中 预测因素 

分 类 号：R743.3[医药卫生—神经病学与精神病学]