非动脉炎性前部缺血性视神经病变危险因素研究进展  

Advances in risk factors for non-arteritic anterior ischemic optic neuropathy

作　　者：刘美娇 张丽琼[1] Mei-Jiao Liu;Li-Qiong Zhang(Department of Ophthalmology,the First Affiliated Hospital of Harbin Medical University,Harbin 150000,Heilongjiang Province,China)

机构地区：[1]哈尔滨医科大学附属第一医院眼科

出　　处：《国际眼科杂志》2020年第2期271-275,共5页International Eye Science

摘　　要：非动脉炎性前部缺血性视神经病变(non-arteritic anterior ischemic optic neuropathy,NAION)是一种严重危害中老年人视功能的急性视神经疾病,一般认为是由于供应视盘筛板区和筛板后区的睫状后短动脉发生缺血所致。该病发生与多种因素相关,如影响全身微循环的糖尿病、高血压和最近研究较多的睡眠呼吸暂停综合征等,再者发现遗传基因易感性、药物、手术和眼部相关疾病都与NAION的发生发展相关。现将这些因素的最新研究进展做一综述。·Non-arteritic anterior ischemic optic neuropathy is an acute optic nerve disease that seriously impairs the visual function of middle-aged and elderly people.It is generally believed to be caused by ischemia of the short ciliary artery supplying the optic disc plate area and the posterior area of the sieve plate.The disease is associated with a variety of factors,such as diabetes that affects the systemic microcirculation,hypertension and respiratory sleep apnea syndrome that has been widely studied recently,and so on.Moreover,it was also found that genetic susceptibility,drugs,surgery and ocular diseases were all associated with the occurrence and development of the NAION.In this paper,the latest researches on these factors are reviewed.

关 键 词：视神经病变 危险因素 缺血性 视乳头 遗传易感性 磷酸二酯酶抑制剂 

分 类 号：R774.6[医药卫生—眼科]