多巴胺及其受体对形觉剥夺近视发展的影响  

Effect of dopamine and its receptors on the development of visual deprivation myopia

作　　者：邓宇 訾迎新[1,2] 秦亚丽 刘自强 农璐琪 金明 Yu Deng;Ying-Xin Zi;Ya-Li Qin;Zi-Qiang Liu;Lu-Qi Nong;Ming Jin(Department of Ophthalmology,China-Japan Friendship Hospital,Beijing 100029,China;Beijing University of Chinese Medicine,Beijing 100029,China;Zhongshan Ophthalmic Center,Sun Yat-sen University,Guangzhou 510060,Guangdong Province,China)

机构地区：[1]中日友好医院眼科,北京市100029 [2]北京中医药大学,北京市100029 [3]中山大学中山眼科中心,广东省广州市,510060

出　　处：《国际眼科杂志》2020年第2期279-281,共3页International Eye Science

摘　　要：我国近视人口已近6亿,青少年近视率居世界第一,近视已成为危害我国居民视力健康的主要疾病之一。多巴胺是视网膜中主要的儿茶酚胺,众多研究发现提高多巴胺含量可有效抑制近视的发展。形觉剥夺是一种经典的近视造模方法,通过观察多巴胺及其受体对形觉剥夺近视发展的影响,可以反映其在近视发展中的作用,对指导控制近视的发生发展具有重要意义。本文就多巴胺及其受体对形觉剥夺性近视发展的影响进行综述,以期为近视的防治提供参考。·Myopic population of China is already nearly 600 million,the rate of teenager myopic occupies the first place in the world,myopia hsa already became one of the main diseases that endangers our adolescent’s health.Dopamine is the main catecholamine in retina.Many studies have found that increasing the content of dopamine can effectively inhibit the development of myopia.Form-deprivation myopia is a classical method of myopia modeling.By observing the influence of dopamine and its receptors on the development of formdeprivation myopia,its role in the development of myopia can be reflected,and it is of great significance to guide and control the occurrence and development of myopia.In this paper,the effects of dopamine and its receptors on the development of form-deprivation myopia were reviewed in order to provide reference for the prevention and treatment of myopia.

关 键 词：多巴胺 多巴胺受体 近视 形觉剥夺 阿扑吗啡 

分 类 号：R778.11[医药卫生—眼科]