不同直径半夏药材的质量差异比较研究  

Comparative Study on the Quality Differences of Pinelliae Rhizoma with Different Diameter

作　　者：赖月月 敬勇[1] 李巧 万子玉 李敏[1] 齐景梁 LAI Yueyue;JING Yong;LI Qiao;WAN Ziyu;LI Min;QI Jingliang(Key Laboratory of Standardization of Chinese Herbal Medicine,Ministry of Education/State Key Laboratory Breeding Base of Systematic Research,Development and Utilization of Chinese Medicine Resources,Chengdu University of TCM,Chengdu 611137,China;Sichuan Institute for Food and Drug Control,Chengdu 611730,China)

机构地区：[1]成都中医药大学中药材标准化教育部重点实验室/中药资源系统研究与开发利用省部共建国家重点实验室培育基地,成都611137 [2]四川省食品药品检验检测院,成都611730

出　　处：《中国药房》2020年第1期29-34,共6页China Pharmacy

基　　金：国家自然科学基金资助项目(No.J1310034-04);国家中药标准化项目(No.ZYBZH-Y-SC-40);四川省科技厅成果转化项目(No.2017CC0084);四川省科技厅科技扶贫项目(No.2017NFP0001,No.2016 NFP0076);四川省教育厅科技成果转化专项(No.42309);四川省教育厅成果转化重大培育项目(No.17CZ0013);中药学学科特色创新团队(No.CXTD2018016)

摘　　要：目的:考察不同直径半夏药材的质量差异,为其资源的合理利用提供参考。方法:以来自国内四大药材市场、2家公司的65批商品半夏为样品,采用游标卡尺测定其直径后,用分药筛将其筛分为不同直径范围(0.5 cm≤d≤0.8 cm、0.8 cm0.05)。73批半夏对口药材的直径主要分布在0.6~1.8 cm之间,平均重量占比为95.54%。若以2015年版《中国药典》(一部)规定的直径标准(1~1.5 cm),73批半夏对口药材中仅8批符合要求,合格率为10.96%;若适当扩大直径范围为0.7~1.5 cm,有54批符合要求,合格率为73.97%;当直径范围扩大为0.7~1.6 cm时,有68批符合要求,合格率达93.15%。结论:不同直径的半夏药材之间质量无明显差异。结合各产地半夏的直径分布情况,可将相关标准中规定的直径大小由"1~1.5 cm"扩大为"0.7~1.6 cm",避免资源浪费。OBJECTIVE:To investigate the quality differences of Pinelliae Rhizoma with different diameter,and to provide reference for the rational utilization of its resources. METHODS:A total of 65 batches of commercial Pinelliae Rhizoma from the four major medicinal markets in China and two companies were collected as samples,the diameter of them were measured by vernier caliper,and then them were screened into samples with different diameter ranges(0.5 cm≤d≤0.8 cm,0.8 cm0.05). The diameter distribution of 73 batches of Pinelliae Rhizoma from corresponding areas was mainly between 0.6 cm and 1.8 cm,with an average weight of 95.54%. If the diameter standard(1-1.5 cm) specified in the 2015 edition of Chinese Pharmacopoeia(part Ⅰ) was adopted,only 8 of 73 batches of Pinelliae Rhizoma meet the requirements,and the qualified rate was 10.96%;if the diameter range was properly expanded to 0.7-1.5 cm,54 batches of Pinelliae Rhizoma meet the requirements,with a qualified rate of73.97%;when the diameter range was expanded to 0.7-1.6 cm,68 batches of Pinelliae Rhizoma meet the requirements,with a qualified rate of 93.15%.CONCLUSIONS:There is no significant difference in the quality of Pinelliae Rhizoma with different diameters. Combined with the diameter distribution of Pinellia Rhizoma in different producing areas,the diameter range of 1-1.5 cm specified in relative standard can be expanded to 0.7-1.6 cm,avoiding the waste of resources.

关 键 词：半夏 有机酸 浸出物 直径 质量 

分 类 号：R282[医药卫生—中药学]