中国女性LEEP与CKC术后妊娠结局比较meta分析  

Meta-analysis of the pregnancy outcomes between LEEP and CKC

作　　者：何君梅[1] 彭慧[1] 刘爽[1] 潘丽萍 邹晓燕[1] He Junmei;Peng Hui;Liu Shuang(The Fifth People's Hospital of Jinan,Jinan 250000)

机构地区：[1]济南市第五人民医院

出　　处：《现代妇产科进展》2020年第2期98-101,共4页Progress in Obstetrics and Gynecology

基　　金：山东省济南市卫生健康委员会重点支持科技计划项目(No:2016-1-11)

摘　　要：目的:比较宫颈环形电切术(LEEP)与冷刀锥切术(CKC)对妊娠结局的影响。方法:检索中国知网、维普、万方、Pubmed、EBSCO和Cochrane图书馆从建库至2019年8月公开发表的有关LEEP与CKC术后妊娠结局比较的有关文献。采用RevMan 5.3进行Meta分析。结果:共纳入25项研究,其中LEEP组1419例、CKC组1082例。Meta分析结果显示,LEEP组的早产、胎膜早破及低体重儿发生率低于CKC组(P<0.00001);LEEP组与CKC组的术后剖宫产发生率比较,差异无统计学意义(P=0.34)。结论:CKC较LEEP对妊娠不良影响大,LEEP术后妊娠相对安全。对于有生育要求的CIN患者,LEEP的治疗优于CKC。Objective:To compare the side effects of loop electrosurgical excision procedure(LEEP) and cold knife conization(CKC) on pregnancy outcomes.Methods:Published articles about the comparison of pregnancy outcomes between LEEP and CKC were searched from CNKI,VIP,Wanfang,Pubmed,EBSCO and Cochrane libraries.During the establishment of the library to Aug.2019.Meta-analysis was performed by RevMan 5.3.Results:25 studies were collected,1419 cases in LEEP group and 1082 cases in CKC group.The results of meta-analysis showed that the incidence of preterm birth,the incidence of premature rupture of membranes,and the incidence of low birth weight in LEEP group were lower than those in CKC group(P<0.00001).The incidence of cesarean section after surgery between LEEP group and CKC group was not statistically significant(P=0.34).Conclusion:CKC has a higher side effect on pregnancy than LEEP.Pregnancy after LEEP is relatively safe.LEEP treatment is superior to CKC in patients with CIN who have fertility requirements.

关 键 词：环形电切术 冷刀锥切术 META分析 

分 类 号：R737.33[医药卫生—肿瘤]