子宫肉瘤22例临床分析  

Clinical analysis of 22 cases of uterine sarcoma

作　　者：马文鹏 李晓丽 MA Wen-peng;LI Xiao-li(Baoji Maternal and Child Health Hospital,Baoji 721000,China)

机构地区：[1]宝鸡市妇幼保健院

出　　处：《临床医学研究与实践》2020年第2期100-102,共3页Clinical Research and Practice

摘　　要：目的探讨子宫肉瘤的临床特征,以提高临床对子宫肉瘤的诊治水平。方法回顾分析2010年1月至2017年12月在我院治疗并有完整记录的22例子宫肉瘤患者的临床资料。结果术后病理证实为子宫平滑肌肉瘤(LMS)10例,子宫内膜间质肉瘤(ESS)8例,子宫恶性苗勒管混合瘤(MMMT)4例。采用FIGO分期,Ⅰ期11例,Ⅱ期7例,Ⅲ期4例,所有病例均行手术治疗,术后辅以化疗或放疗,部分给予激素及靶向治疗。子宫肉瘤患者3、5年总体生存率分别为73%、45%。结论子宫肉瘤以LMS+ESS发生率较高,临床给予以手术为主的综合治疗以改善患者的预后并提高生存率。Objective To explore the clinical characteristics of uterine sarcoma, in order to improve the level of clinical diagnosis and treatment of uterine sarcoma. Methods The clinical data of 22 patients with uterine sarcoma treated in our hospital and had full record from January 2010 to December 2017 were analyzed retrospectively. Results Postoperative pathology confirmed 10 cases of leiomyosarcoma(LMS), 8 cases of endometrial stromal sarcoma(ESS), and 4 cases of malignant mixed mullerian tumor(MMMT). FIGO was used for staging, 11 cases in stage Ⅰ, 7 cases in stage Ⅱ and 4 cases in stage Ⅲ. All cases were treated with surgery, followed by chemotherapy or radiotherapy, and some patients were treated with hormone and targeted therapy. The 3-year and 5-year overall survival rates were 73% and 45%, respectively.Conclusion The incidence of LMS + ESS is higher in uterine sarcomas, and the comprehensive treatment based on surgery is given to improve the prognosis and survival rate of patients in clinic.

关 键 词：子宫肉瘤 子宫平滑肌肉瘤 子宫内膜间质肉瘤 子宫恶性苗勒管混合瘤 靶向治疗 

分 类 号：R737.33[医药卫生—肿瘤]