胃肠道腺癌18F-FDG PET-CT标准摄取值与ADC值的相关性分析  

Correlation analysis between SUV with 18F-FDG PET-CT and ADC value in gastrointestinal tract adenocarcinma

作　　者：王琪 汪秀玲 王珍 高晶晶 Wang Qi;Wang Xiuling;Wang Zhen;Gao Jingjing(Department of Imaging,Affiliated Hospital of Xuzhou Medical University,Xuzhou 221000,China)

机构地区：[1]徐州医科大学附属医院影像科,江苏徐州221000

出　　处：《中国中西医结合影像学杂志》2020年第1期47-50,共4页Chinese Imaging Journal of Integrated Traditional and Western Medicine

摘　　要：目的:利用PET-CT-MRI三模式,分析胃肠道腺癌多b值DWI单指数及双指数模型的ADC值与脱氧葡萄糖(FDG) PET-CT中标准摄取值(SUV)之间的相关性。方法:连续选择29例未经治疗的胃肠道腺癌患者,均行PET-CT及MRI检查。胃肠道腺癌标准摄取值的最大值(SUVmax)与单指数及双指数模型ADC值行Pearson相关性分析。结果:胃肠道腺癌的SUVmax与多指数模型的慢速表观扩散系数(ADCslow)呈显著负相关(r=-0.677,P=0.000)。结论:胃肠道腺癌PET-CT的参数SUVmax与双指数模型的ADCslow值有相关性,提示胃肠道腺癌的葡萄糖代谢与水分子弥散间有一定关系。Objective:The aim of the study was to evaluate quantitative correlation between SUV with 18F-FDG PET-CT and ADC value of mono-exponential model and dual-exponential model with multi b value DWI in gastrointestinal tract adenocarcinma. Methods:Twenty-nine consecutive patients with gastrointestinal tract adenocarcinma were included in this study,who all carried out 18F-FDG PET/CT and MRI. Pearson correlation test was used to detect the relationships between SUV and ADC of mono-exponential model and dual-exponential model of primary gastrointestinal tract malignant tumor. Results:Significant negative correlations were found between SUV and ADCslow(r=-0.677,P= 0.000) in gastrointestinal tract adenocarcinma. Conclusion:SUV,parameter in PET,has correlation with ADCslow in DWI,which represents there is a certain relationship between glucose metabolism and diffusion of water molecules with gastrointestinal tract adenocarcinoma.

关 键 词：胃肠道 腺癌 磁共振成像 弥散 正电子发射断层显像术 

分 类 号：R735[医药卫生—肿瘤] R730.44[医药卫生—临床医学]