18F-FDG PET/CT联合薄层螺旋CT三维重建诊断孤立性肺结节  

18F-FDG PET/CT combined with three-dimensional reconstruction of thin-slice helical CT in diagnosis of solitary pulmonary nodules

作　　者：陈国强[1] 苏福[1] 王卫星[1] 马超[1] CHEN Guoqiang;SU Fu;WANG Weixing;MA Chao(Department of Nuclear Medicine,Zhongshan Hospital Xiamen University,Xiamen 361004,China)

机构地区：[1]厦门大学附属中山医院核医学科

出　　处：《中国医学影像技术》2020年第1期86-90,共5页Chinese Journal of Medical Imaging Technology

基　　金：福建省卫计委青年科研项目(2015-2-46);厦门市科技局科技计划项目(3502Z20164021)

摘　　要：目的观察18 F-FDG PET/CT联合薄层螺旋CT三维重建对孤立性肺结节(SPN)的诊断价值。方法对139例SPN患者采用18 F-FDG PET/CT常规扫描后行肺部薄层螺旋CT扫描和三维重建,对比分析18 F-FDG PET/CT联合薄层螺旋CT三维重建和单独诊断SPN的准确率。结果139例SPN,经病理证实恶性83例、良性48例,8例经临床抗感染治疗病灶变小或消失而诊断为良性SPN。PET/CT联合薄层CT三维重建诊断SPN的灵敏度85.71%(72/84)、特异度78.18%(43/55),诊断符合率82.73%(115/139),均高于单独18 F-FDG PET/CT[64.29%(54/84)、54.55%(30/55)及60.43%(84/13)]。结论联合CT三维重建能明显提高18 F-FDG PET/CT诊断SPN的准确率。Objective To explore the value of 18 F-FDG PET/CT combined with three-dimensional reconstruction of thin-slice spiral CT in diagnosis of solitary pulmonary nodules(SPN).Methods A total of 139 patients with SPN were selected.After routine 18 F-FDG PET/CT scanning,thin-slice spiral CT scanning and three-dimensional reconstruction were performed.The accuracy of single 18 F-FDG PET/CT and 18 F-FDG PET/CT combined with three-dimensional reconstruction of thin-slice spiral CT in diagnosis of SPN were recorded and compared.Results Totally 139 SPN were pathologically confirmed after operation or puncture,including 83 malignant and 48 benign ones.SPN in 8 patients became small or disappeared after clinical anti-inflammatory treatment,and thus were diagnosed as benign ones.The sensitivity,specificity and coincidence rate of combined diagnosis of SPN nodules was 85.71%(72/84),78.18%(43/55)and 82.73%(115/139),respectively,all higher than of single 18 F-FDG PET/CT(64.29%[54/84],54.55%[30/55]and 60.43%[84/139],respectively).Conclusion 18 F-FDG PET/CT combined with three-dimensional reconstruction of thin-slice spiral CT can significantly improve the accuracy for diagnosing SPN.

关 键 词：孤立性肺结节 正电子发射断层显像术 薄层扫描 三维重建 

分 类 号：R734.2[医药卫生—肿瘤] R817.4[医药卫生—临床医学]