胃肠胰神经内分泌肿瘤诊治进展  

Current development of diagnosis and treatments in neuroendocrine neoplasm

作　　者：梁家奎 王杰[1] 嵇晋 阳媚媛 王道荣 Liang Jiakui;Wang Jie;Ji Jin;Yang Meiyuan;Wang Daorong(Department of General Surgery,General Surgery Institute of Yangzhou,Clinical Medical College,Yangzhou University,Yangzhou 225000,China;Department of General Surgery,the Second Xiangya Hospital of Central South University,Changsha 410000,China;Department of General Surgery,Clinical Medical College,Yangzhou University,Northern Jiangsu Province Hospital,General Surgery Institute of Yangzhou,Yangzhou 225000,China)

机构地区：[1]扬州大学医学院,225000 [2]中南大学湘雅二医院普外科,长沙410000 [3]扬州大学附属苏北医院(江苏省苏北人民医院)胃肠中心,扬州大学-扬州市普通外科研究所,胃肠外科,225000

出　　处：《中华腔镜外科杂志（电子版）》2019年第6期380-384,共5页Chinese Journal of Laparoscopic Surgery(Electronic Edition)

基　　金：江苏省第五期“333工程”高层次人才培养专项(BRA2017153)

摘　　要：神经内分泌肿瘤(neuroendocrine neoplasm,NEN)是一类肽能神经元以及神经内分泌细胞起源的、具有神经内分泌标记物、能够产生生物活性胺和(或)多肽激素类物质的异质性肿瘤。NEN好发于消化系统,尤其好发于胃肠胰等器官,肝脏、肺和骨则为NEN的转移好发部位。NEN尽管发病率较低,但由于其起病隐匿、缺乏明显的临床特异性等原因,通常该类患者的预后较差。笔者对目前国内外NEN在诊断、治疗等方面的最新进展作一总结回顾,为NEN的诊治提供参考。Neuroendocrine neoplasm arises from cells of the endocrine and nervous systems with functions of producing active amine and hormones.Most of NEN occur in digestive system especially in stomach,intestines and pancreas.The liver,lung and bone are the most common place for metastatic NEN.Because of lacking of specific symptoms,the prognosis of NEN is usually poor.The present study aimed at concluding at current diagnosis and treatment for NEN,providing references for patients with NEN.

关 键 词：胃肠道 胰腺 神经内分泌肿瘤 

分 类 号：R735[医药卫生—肿瘤]