卵巢卵黄囊瘤手术和化疗后自然周期体外受精-胚胎移植成功分娩一例并文献复习  

Case Report about a Successful Delivery by the Natural Cycle of IVF-ET after the Operation and Chemical Treatment of Ovarian Yolk Sac Tumor, and Literature Review

作　　者：李娅[1] 白晓红[1] 赵晓徽[1] LI Ya;BAI Xiao-hong;ZHAO Xiao-hui(Department of Obstetrics and Gynecology,Tianjin Medical University General Hospital,Tianjin 300052,China)

机构地区：[1]天津医科大学总医院妇产科

出　　处：《国际妇产科学杂志》2020年第1期81-84,共4页Journal of International Obstetrics and Gynecology

摘　　要：卵巢卵黄囊瘤属卵巢恶性生殖细胞肿瘤,占卵巢恶性肿瘤的1%。由于卵巢恶性生殖细胞肿瘤多见于儿童及年轻女性,故保存生育能力是关键。卵巢卵黄囊瘤对化疗药物敏感,手术联合术后辅助化疗是标准治疗方案。对于对侧卵巢和子宫未受肿瘤累及,并且有生育需求的患者均应行保留生育功能的手术。但肿瘤本身、手术和放化疗均可能造成患者不孕,术后可能需要借助辅助生殖技术助孕,本文通过1例卵巢卵黄囊瘤患者手术和术后化疗后行自然周期-体外受精-胚胎移植(NC-IVF-ET)的个案报道和文献复习,探讨卵巢卵黄囊瘤患者的生育助孕策略。Ovarian yolk sac tumor is a kind of ovarian malignant germ cell tumor, accounting for 1% of ovarian malignant tumors. As malignant ovarian germ cell tumors are more common in children and young women, fertility preservation is the key.Ovarian yolk sac tumor is sensitive to chemotherapeutic drugs. Operation combined with postoperative adjuvant chemotherapy is the standard treatment. For the contralateral ovary and uterus not affected by tumor, fertility preservation surgery should be carried out.However, the tumor itself, surgery and chemoradiotherapy may cause infertility in patients, assisted reproductive technology may be needed after surgery. In this paper, through a case report of a patient with ovarian yolk sac tumor undergoing NC-IVF-ET after surgery and postoperative chemotherapy and literature review, the fertility assisted strategy of patients with ovarian yolk sac tumor was discussed.

关 键 词：卵巢卵黄囊瘤 卵巢肿瘤 内胚层窦瘤 生育力 药物疗法 联合 体外受精 胚胎移植 

分 类 号：R737.31[医药卫生—肿瘤] R714.8[医药卫生—临床医学]