Endoscopic Kyoto classification of Helicobacter pylori infection and gastric cancer risk diagnosis  

作　　者：Osamu Toyoshima Toshihiro Nishizawa Kazuhiko Koike 

机构地区：[1]Department of Gastroenterology,Toyoshima Endoscopy Clinic,Tokyo 157-0066,Japan [2]Department of Gastroenterology,Graduate School of Medicine,The University of Tokyo,Tokyo 113-8655,Japan [3]Department of Gastroenterology and Hepatology,International University of Health and Welfare,Mita Hospital,Tokyo 108-8329,Japan

出　　处：《World Journal of Gastroenterology》2020年第5期466-477,共12页世界胃肠病学杂志（英文版）

摘　　要：Recent advances in endoscopic technology allow detailed observation of the gastric mucosa.Today,endoscopy is used in the diagnosis of gastritis to determine the presence/absence of Helicobacter pylori(H.pylori)infection and evaluate gastric cancer risk.In 2013,the Japan Gastroenterological Endoscopy Society advocated the Kyoto classification,a new grading system for endoscopic gastritis.The Kyoto classification organized endoscopic findings related to H.pylori infection.The Kyoto classification score is the sum of scores for five endoscopic findings(atrophy,intestinal metaplasia,enlarged folds,nodularity,and diffuse redness with or without regular arrangement of collecting venules)and ranges from 0 to 8.Atrophy,intestinal metaplasia,enlarged folds,and nodularity contribute to gastric cancer risk.Diffuse redness and regular arrangement of collecting venules are related to H.pylori infection status.In subjects without a history of H.pylori eradication,the infection rates in those with Kyoto scores of 0,1,and≥2 were 1.5%,45%,and 82%,respectively.A Kyoto classification score of 0 indicates no H.pylori infection.A Kyoto classification score of 2 or more indicates H.pylori infection.Kyoto classification scores of patients with and without gastric cancer were 4.8 and 3.8,respectively.A Kyoto classification score of 4 or more might indicate gastric cancer risk.Recent advances in endoscopic technology allow detailed observation of the gastric mucosa. Today, endoscopy is used in the diagnosis of gastritis to determine the presence/absence of Helicobacter pylori(H. pylori) infection and evaluate gastric cancer risk. In 2013, the Japan Gastroenterological Endoscopy Society advocated the Kyoto classification, a new grading system for endoscopic gastritis. The Kyoto classification organized endoscopic findings related to H.pylori infection. The Kyoto classification score is the sum of scores for five endoscopic findings(atrophy, intestinal metaplasia, enlarged folds, nodularity,and diffuse redness with or without regular arrangement of collecting venules)and ranges from 0 to 8. Atrophy, intestinal metaplasia, enlarged folds, and nodularity contribute to gastric cancer risk. Diffuse redness and regular arrangement of collecting venules are related to H. pylori infection status. In subjects without a history of H. pylori eradication, the infection rates in those with Kyoto scores of 0, 1, and ≥ 2 were 1.5%, 45%, and 82%, respectively. A Kyoto classification score of 0 indicates no H. pylori infection. A Kyoto classification score of 2 or more indicates H. pylori infection. Kyoto classification scores of patients with and without gastric cancer were 4.8 and 3.8, respectively. A Kyoto classification score of 4 or more might indicate gastric cancer risk.

关 键 词：Gastric cancer Helicobacter pylori Endoscopy Kyoto classification Atrophy Intestinal metaplasia Enlarged fold NODULARITY Diffuse redness Regular arrangement of collecting venules 

分 类 号：R735.2[医药卫生—肿瘤]