南京口岸来华留学生麻疹、腮腺炎、风疹、水痘抗体监测结果分析  

Surveilliance Antibody Levels of Measles,Mumps,Rubella and Varicella in International Students Entering Nanjing Port

作　　者：田玲玲[1] 杨国平[2] 陈琳 朱军[2] 郭晔[2] 吴媛媛 姜宏[2] 林君宜 吴海磊 Tian Lingling;Yang Guoping;Chen Lin;Zhu Jun;Guo Ye;Wu Yuanyuan;Jiang Hong;Lin Junyi;Wu Hailei(Jiangsu International Travel Healthcare Center,Nanjing Medical University,Nanjing,Jiangsu,210000;Jiangsu International Travel Healthcare Center,Nanjing,Jiangsu,210000;Yangzhou Branch of Jiangsu International Ttravel Healthcare Center,Nanjing,Jiangsu,225000;Nanjing Customs,Nanjing,Jiangsu,210000)

机构地区：[1]江苏国际旅行卫生保健中心,南京医科大学,江苏南京210000 [2]江苏国际旅行卫生保健中心,江苏南京210000 [3]苏国际旅行卫生保健中心扬州分中心,江苏扬州225000 [4]南京海关,江苏南京210000

出　　处：《口岸卫生控制》2019年第6期46-50,55,共6页Port Health Control

基　　金：南京海关立项课题（2018KJ39）

摘　　要：目的了解/掌握高校入境留学生麻疹、腮腺炎、风疹、水痘等主要呼吸道传播疾病的血清抗体水平,为加强口岸疾病防控提供依据。方法收集2018-2019年南京口岸高校来华留学生中选取来自十大生源国及6个非洲国家学生健康体检资料共计270份,采用ELISA方法抽样检测麻疹、腮腺炎、风疹、水痘等血清抗体水平,并对结果进行统计学分析。结果来华留学生麻疹抗体总体阳性率为80%,总体保护率为35.21%,泰国、印度、加纳、尼日利亚、津巴布韦、肯尼亚等国家学生抗体阳性率较低;日本学生麻疹抗体保护率最高,为72.22%,印度尼西亚学生次之,为66.67%,其余各国学生麻疹抗体保护率均不高于50%;腮腺炎总体抗体阳性率为80.37%,俄罗斯、哈萨克斯坦、泰国、埃塞俄比亚、尼日利亚、印度尼西亚、老挝等国学生阳性率较低;风疹抗体总体阳性率为87.04%,泰国、俄罗斯等国学生阳性率较低;水痘抗体总体阳性率为87.78%,印度、埃塞俄比亚、哈萨克斯坦、老挝等国学生阳性率较低。结论来华留学生中麻疹、腮腺炎、风疹、水痘等抗体阳性率不高,存在感染风险,应通过加强健康宣教提高其防病意识,加强高危人群和低保护率国家的血清抗体水平监测,必要时可以对其进行疫苗补种以提高对疾病的免疫力。Objective To investigate the seroprevalence of Measles,Mumps,Rubella and Varicella among international students in China,and provide the scientific basis for prevention and control of these infectious dieseases.Methods A total of 270 samples of international students study in universities in Nanjing during 2018-2019 from the top 10 largest countries and 6 African countries was collected.Seroprevalence of Measles,Mumps,Rubella and Varicella was detected by ELISA,and were assessed for an epidemiological analysis.Results The overall positive rate of the Measles antibody in the international students was 80%,and protection rate was 35.21%.The respective rate of the Measles antibody in the international students from Thailand,India,Ghana,Nigeria,Zimbabwe and Kenya was no more than 80.00%.The protection rate of the Measles antibody was high in the students from Japan(72.22%)and Indonesia(66.67%),while it was no more than 50%in the students from all the other countries.The overall positive rate of the Mumps antibody was 80.37%,with respective rate was lower than 80.00%in the students from Russia,Kazakhstan,Thailand,Ethiopia,Nigeria,Indonesia and Lao.The overall rate of the Rubella antibody was 87.04%,with respective rate was lower than 80.00%in the students from Thailand and Russia.The overall positive rate of Varicella was 87.78%,with respective rate was lower than 80.00%in the students from India,Ethiopia,Kazakhstan,Lao.Conclusion The positive rate of the Measles,Mumps,Rubella and Varicella was low.There is risk for the international students to be infectious to the Measles,Mumps,Rubella and Varicella.Measures should be taken to strengthen the awareness of diseases prevention and enhance the monitoring the seroprevalence among people in high risk or from countries with low protection.Vaccines should be used to protect them against the diseases when necessary.

关 键 词：来华留学生 麻疹 腮腺炎 风疹 水痘 抗体水平 

分 类 号：R51[医药卫生—内科学]