倒班工作睡眠障碍患者的注意网络功能研究  

Study on attention networks in patients with shift work sleep disorder

作　　者：刘玉莲[1] 贾竑晓[1] 宋楠 姚昊 宁艳哲 Liu Yulian;Jia Hongxiao;Song Nan;Yao Hao;Ning Yanzhe(Beijing Anding Hospital,Capital Medical University,Beijing Institute of Schizophrenia Major Brain Disease Research Institute,Mental Illness Diagnosis and Treatment Beijing Key Laboratory,Beijing 100088,China)

机构地区：[1]首都医科大学附属北京安定医院国家精神心理疾病临床研究中心精神疾病诊断与治疗北京市重点实验室

出　　处：《首都医科大学学报》2020年第1期71-74,共4页Journal of Capital Medical University

基　　金：国家自然科学基金项目(81904120,81873398);北京中医药科技发展基金青年项目(QN2018-27);北京市医院管理中心“登峰”计划(DFL20191901);首都医科大学科研培育基金(PYZ2018146)~~

摘　　要：目的评估倒班工作睡眠障碍患者注意网络受损情况。方法对30例倒班工作睡眠障碍患者和26例规律睡眠健康对照进行注意网络测试。结果与规律睡眠健康受试者相比,倒班工作睡眠障碍患者在警觉网络效率(P<0.01)和执行控制网络效率方面明显下降(P<0.01),定向网络效率、平均反应时间和平均正确率与正常对照组相比则差异无统计学意义(P>0.05);执行控制网络效率与匹兹堡睡眠质量指数总分成正比(r=0.58,P=0.001)。结论倒班工作睡眠障碍患者警觉网络和执行网络受损,定向网络保留。Objective To study the impairment of attention networks in patients with shift work sleep disorder(SWSD).Methods A total of 30 patients with SWSD and 26 matched healthy subjects were recruited to undergo attention network test(ANT).Results Compared with healthy subjects,the patients with SWSD showed significantly poorer efficiency on alerting attention and executive attention(P<0.01).Furthermore,efficiency on executive attention was positively associated with the scores of Pittsburgh sleep quality index(PSQI).Conclusion Our findings suggest that patients with SWSD exhibited selective impairments of attention network of alerting and executive control.

关 键 词：倒班工作睡眠障碍 注意网络 功能评估 

分 类 号：R749.7[医药卫生—神经病学与精神病学]