中心型肺癌支气管动脉介入方法和血管构型与近期疗效对比分析  

Correlation of bronchial artery intervention and vascular configuration with short-term treatment effects of central lung cancer

作　　者：张守民[1] 陈照亮[2] 高国政[1] Zhang Shoumin;Chen Zhaoliang;Gao Guozheng(Department of Radiology,Binzhou Central Hospital,Binzhou 251700,China;Department of Oncology,Binzhou Central Hospital,Binzhou 251700,China)

机构地区：[1]滨州市中心医院影像中心,251700 [2]滨州市中心医院肿瘤科,251700

出　　处：《国际医药卫生导报》2020年第2期216-219,共4页International Medicine and Health Guidance News

摘　　要：目的探讨中心型肺癌支气管动脉介入方法和血管构型与疗效的关系。方法回顾分析本院69例支气管动脉介入治疗中心型肺癌患者的近期疗效,其中39例患者采取“三明治”式支气管动脉栓塞化疗,包括富血管型28例,乏血管型11例;另30例患者采取单纯支气管动脉灌注化疗,包括富血管型21例,乏血管型9例。疗程结束后定期评价其疗效。结果39例支气管动脉栓塞化疗者有效29例,有效率74.36%(29/39),其中28例富血管型患者有效23例,11例乏血管型患者有效6例;30例支气管动脉灌注化疗者有效14例,有效率46.67%(14/30),其中21例富血管型患者有效12例,9例乏血管型患者有效2例。结果显示,支气管动脉栓塞化疗中心型肺癌其疗效明显优于支气管动脉灌注化疗,疗效差异有统计学意义(P<0.05);支气管动脉栓塞化疗和灌注化疗富血管型中心型肺癌其疗效明显优于乏血管型,差异有统计学意义(P<0.05)。治疗中未发生严重并发症。结论支气管动脉介入治疗中心性肺癌优先选择栓塞化疗术,疗效好,见效快,对富血管型肺癌疗效更显著。Objective To explore the correlation bronchial artery intervention and vascular configuration with short-term treatment effects of central lung cancer.Methods The short-term effects of 69 patients with central lung cancer treated by bronchial artery intervention in our hospital were retrospectively analyzed.39 patients,including 28 cases of hypervascular and 11 cases of hypovascular,were treated with“sandwich”bronchial artery chemoembolization;and the other 30 patients,including 21 cases of hypervascular and 9 cases of hypovascular,were treated with simple bronchial artery infusion chemotherapy.At the end of the course,the effects were regular assessed.Results Among the 39 patients,bronchial artery chemoembolization was effective in 29 patients,with a response rate(RR)of 74.36%(29/39)——and it was effective in 23 cases among the 28 hypervascular cases and in 6 cases among the 11 hypovascular cases.Among the 30 patients,bronchial artery infusion chemotherapy was effective in 14 patients,with a RR of 46.67%(14/30)——it was effective in 12 cases among the 21 hypervascular cases and in 2 cases among the 9 hypovascular cases.The results showed that bronchial artery chemoembolization had better effects than bronchial artery infusion chemotherapy in the treatment of central lung cancer,and the difference was statistically significant(P<0.05);bronchial artery chemoembolization and infusion chemotherapy had better effects in the treatment of hypervascular central lung cancer than hypovascular central lung cancer,and the difference was statistically significant(P<0.05).No serious complications occurred during the treatment.Conclusion In terms of bronchial artery intervention for treating central lung cancer,chemoembolization is preferred,for it has good and quick effects and is more effective in the treatment of hypervascular lung cancer.

关 键 词：中央型肺癌 支气管动脉介入 血管构型 

分 类 号：R734[医药卫生—肿瘤]