PET/CT和MRI在多发性骨髓瘤诊断中的应用价值及影像表现分析  

Application Value and Imaging Findings of PET/CT and MRI in the Diagnosis of Multiple Myeloma

作　　者：周存凉[1] 丁勇生[1] 沈月红[1] ZHOU Cun-liang;DING Yong-sheng;SHEN Yue-hong(Department of Radiology,Nantong Cancer Hospital,Nantong 226006,Jiangsu Province,China)

机构地区：[1]江苏省南通市肿瘤医院影像科

出　　处：《中国CT和MRI杂志》2019年第12期143-145,152,共4页Chinese Journal of CT and MRI

摘　　要：目的探究正电子发射计算机断层显像(PET/CT)和磁共振成像(MRI)在多发性骨髓瘤(MM)诊断中的应用价值并分析其影像学表现。方法选择2016年12月到2018年3月到医院就诊MM患者55例,所有患者均进行MRI、PET/CT检查。统计MM在MRI、PET/CT中影像学表现,统计MRI、PET/CT的诊断效能,统计MRI、PET/CT对不同类型MM检出率,统计MRI、PET/CT对MM分期情况(与病理检测结果比较)。结果MRI影像表现为MM患者在常规T1WI序列上表现为低信号,并在T2WI序列上表现为高信号;PET/CT影像表现为骨髓弥漫型患者多处骨质摄取FDG不均匀,骨质破坏型患者病灶处可见异常18F-FDG摄取浓聚,髓外病变型患者显示全身骨质对FDG存在不同程度摄取;PET/CT诊断准确率、灵敏度均高于MRI,差异有统计学意义(P<0.05);PET/CT在骨质破坏型检出率高于MRI,差异有统计学意义(P<0.05);MRI、PET/CT对MM分期情况无明显差异,差异无统计学意义(P>0.05)。结论PET/CT诊断MM准确率、灵敏度更高,对骨质破坏型MM检出率更高。Objective To analyze the application value and imaging findings of positron emission computer tomography(PET/CT)and magnetic resonance imaging(MRI)in the diagnosis of multiple myeloma(MM).Methods 55 cases of patients with MM in the hospital from December 2016 to March 2018 were selected and given MRI and PET/CT.The imaging findings of MM in MRI and PET/CT were counted,and the diagnostic efficacy of MRI and PET/CT were counted,and the detection rates of different types of MM by MRI and PET/CT were counted.The results were compared with pathological detection results,and the MM staging by MRI and PET/CT was counted.Results MRI images showed that MM patients showed low signal on conventional T1WI sequence and high signal on T2WI sequence.PET/CT images showed uneven FDG bone intake in patients with diffuse bone marrow,and abnormal increased 18F-FDG uptake was observed in the lesions of patients with bone destruction,and patients with extramedullary lesions showed different degrees of FDG uptake.The accuracy and sensitivity of PET/CT were higher than those of MRI(P<0.05).The detection rate of bone destruction by PET/CT was higher than that by MRI(P<0.05).There were no significant differences in MM staging by MRI or PET/CT(P>0.05).Conclusion The accuracy and sensitivity of PET/CT were higher in the diagnosis of MM,and it has higher detection rate of bone destruction type of MM.

关 键 词：磁共振成像 正电子发射计算机断层显像 多发性骨髓瘤 诊断 

分 类 号：R733.3[医药卫生—肿瘤] R445.2[医药卫生—临床医学]