内镜下乳头括约肌切开术致Oddi括约肌功能损伤的研究现状  

Research advances in the impairment of Oddi sphincter function caused by endoscopic sphincterotomy

作　　者：王军民 任威瑞 孟霞[1] 赵丽伟[1] 江涛 WANG Junmin;REN Weirui;MENG Xia(Department of Gastroenterology, Third Hospital of Hebei Medical University, Shijiazhuang 050000, China)

机构地区：[1]河北医科大学第三医院消化内科,石家庄050000 [2]涉县人民医院消化内科,河北邯郸056400

出　　处：《临床肝胆病杂志》2020年第2期468-471,共4页Journal of Clinical Hepatology

基　　金：河北省重点研发计划项目(19277729D)

摘　　要：Oddi括约肌结构精巧,其功能的完整性对于防止十二指肠内容物反流及细菌等逆行感染,维护肝胆胰内外部生理环境的平衡具有不可替代的作用。内镜下乳头括约肌切开术破坏了Oddi括约肌的完整性,其造成的负效应受到了越来越多的关注。概述了内镜下乳头括约肌切开术致Oddi括约肌功能损伤的研究进展,认为临床医师需正确认识和重视内镜下乳头括约肌切开术致Oddi括约肌功能的损伤,从多角度综合分析,根据患者的具体情况制订合理化诊疗方案。The Oddi sphincter has a delicate structure, and the integrity of its function has an irreplaceable role in preventing retrograde infection due to the reflux of duodenal contents and bacteria and maintaining the balance of physiological environment inside and outside the liver, the pancreas, and the gallbladder. Endoscopic sphincterotomy impairs the integrity of the Oddi sphincter, and such negative effects have received more and more attention. This article reviews the research advances in the impairment of Oddi sphincter function caused by endoscopic sphincterotomy and points out that clinicians should understand and attach importance to such impairment, perform a comprehensive analysis from various aspects, and develop reasonable diagnosis and treatment regimens based on patient’s own conditions.

关 键 词：胆总管结石 奥狄括约肌 括约肌切开术 内窥镜 

分 类 号：R575.7[医药卫生—消化系统]