分析全胸段食管切除与胸中下段食管切除对食管癌患者术后生存率的影响  

Analysis of the effect of total thoracic esophageal resection and lower thoracic esophageal resection on postoperative survival in patients with esophageal cancer

作　　者：穆小飞 蔡晓敏 刘虎[2] 杨琳 Mu Xiaofei;Cai Xiaomin;Liu Hu;Yang Lin(Department of Oncology,Xinjiang Yili State Friendship Hospital,Yili,Xinjiang,835000,China;Department of Thoracic Surgery,Xinjiang Yili State Friendship Hospital,Yili,Xinjiang,835000,China)

机构地区：[1]新疆伊犁州友谊医院肿瘤科,新疆伊犁835000 [2]新疆伊犁州友谊医院胸心外科,新疆伊犁835000

出　　处：《当代医学》2020年第6期23-25,共3页Contemporary Medicine

基　　金：新疆伊犁州级课题（YZ201701029）

摘　　要：目的探讨全胸段食管切除与胸中下段食管切除对食管癌患者术后生存率的影响。方法选取1996年至2016年伊犁州友谊医院、新华医院、兵团农四师医院、解放军第十一医院收治的1906例食管癌患者,其中Ⅰ组患者680例为左胸后外侧切口,Ⅱ组患者694例为左颈切口及左胸后外侧切口,Ⅲ组患者532例为三切口,所有患者均接受食管癌食管切除术及食管床食管重建术。结果1906例食管癌患者,随访率74.5%,失访486例,Ⅰ组患者术后第1年生存率为67.13%,第3年生存率为32.44%,第5年生存率为26.52%,第10年生存率为6.52%,Ⅱ组患者术后第1年生存率为62.53%,第3年生存率为35.35%,第5年生存率为21.08%,第10年生存率为6.17%,Ⅲ组患者术后第1年生存率为65.13%,第3年生存率为31.23%,第5年生存率为25.05%,第10年生存率为6.23%,所有患者术后第1年和第3年生存率比较差异无统计学意义,Ⅰ组与Ⅲ组5年生存率比较差异具有统计学意义(P<0.05);而Ⅰ组、Ⅱ组、Ⅲ组5~10年生存率比较差异无统计学意义。结论胸下段食管癌患者通过左胸后外侧切口、左颈切口及左胸后外侧切口及三切口三种手术入路进行治疗,三切口5年生存率明显比左胸后外侧切口更高,左颈切口及左胸后外侧切口长期生存率也呈不断上升趋势,因此,在胸下段食管癌患者治疗时,可采取三切口手术入路进行治疗以提高患者术后生存率。Objective To investigate the effects of total thoracic esophageal resection and lower thoracic esophageal resection on postoperative survival in patients with esophageal cancer.Methods From 1996 to 2016,1906 patients with esophageal cancer were admitted to Yili Friendship Hospital,Xinhua Hospital,Bingtuan Agricultural Fourth Division Hospital,and the 11th Hospital of the People's Liberation Army.Among them,680 patients in Group I were left chest and lateral incisions.In groupⅡ,694 cases were left neck incision and left thoracic posterior lateral incision,and in groupⅢ,532 cases were three incision.All patients received esophageal esophagealesophageal resection and esophageal esophageal reconstruction.Results In 1906 patients with esophageal cancer,the follow-up rate was 74.5%,and 486 cases were lost.The first year survival rate was 67.13%,the third year survival rate was 32.44%,the fifth year survival rate was 26.52%,the 10th year survival rate was 6.52%,the first year survival rate was 62.53%,and the third year survival rate was 35.35%.The survival rate was 21.08%in the fifth year,6.17%in the tenth year,65.13%in the first year after surgery,31.23%in the third year,and 25.05%in the fifth year.The survival rate was 6.23%in the tenth year.There was no significant difference between the first and third years after surgery in all patients.The difference between the five-year survival rate of group I and groupⅢwas statistically significant(P<0.05);There was no significant difference in the performance of 5 to 10 years survival in GroupⅠ,GroupⅡand GroupⅢ.Conclusion The patients with subthoracic esophageal carcinoma were treated by left posterior lateral incision,left neck incision,left pos‐terior lateral incision and three incision.The 5-year survival rate of three incision was significantly higher than that of left posterior lateral incision.The long-term survival rate of left neck incision and left thoracic posterior lateral incision also showed an increasing trend.Therefore,when treating patients with

关 键 词：全胸段食管切除 胸中下段食管切除 食管癌 术后生存率 

分 类 号：R735.1[医药卫生—肿瘤]